Surface characterization of nanoparticles using near-field light scattering

• Eunsoo Yoo,
• Yizhong Liu,
• Chukwuazam A. Nwasike,
• Sebastian R. Freeman,
• Brian C. DiPaolo,
• Bernardo Cordovez and
• Amber L. Doiron

Beilstein J. Nanotechnol. 2018, 9, 1228–1238, doi:10.3762/bjnano.9.114

• )-coated superparamagnetic iron oxide nanoparticles (PEG-SPIOs) with the synthetic pseudotannin polygallol via interpolymer complexation (IPC). Changes in particle size and zeta potential were indirectly assessed via differences between PEG-SPIOs and IPC-SPIOs in particle velocity and scattering intensity

• iron oxide nanoparticles (IPC-SPIOs). Nanophotonic force microscopy pushes particles against a waveguide surface, optically trapping the particles by light confinement [10][19][20]. The evanescent fields are created by the waveguide, and there are four forces operating on the field: the gradient force

• on the waveguide. Superparamagnetic iron oxide nanoparticles (SPIOs) have been extensively studied due to their unique chemical, physical, thermal, and mechanical applications in areas such as cell labeling, tissue repair, drug delivery, magnetic resonance (MR) contrast, and hyperthermia [25][26][27

Multiwalled carbon nanotube hybrids as MRI contrast agents

• Nikodem Kuźnik and
• Mateusz M. Tomczyk

Beilstein J. Nanotechnol. 2016, 7, 1086–1103, doi:10.3762/bjnano.7.102

• introduced in the form of diethylene triamine pentaacetic acid (DTPA) complexes (classical CAs) on SWCNTs [16], superparamagnetic iron oxides (SPIOs) were anchored on SWCNTs [6] and, on the contrary, iron-deficient SWCNTs [17] were found to exhibit good properties for potential MRI CAs. These first works in

• nanoparticles belong to the group of SPIOs known as MRI CAs [46][47], while the resulting behavior after coupling with MWCNT is determined as an entire, new SPIO–MWCNT hybrid. More thorough studies of SPIO impact on the properties and biocompatibility of hybrids should be encouraged. Magnetic properties The

• . Magnetic hysteresis loops close to zero magnetization in a varied magnetic field is typical behavior proving the super- [34][43] or paramagnetic [22] character of the introduced nanoparticles. Initially, the separately produced SPIOs, such as SPIO@Lac-Gly, exhibit higher magnetization, but their anchoring

The distribution and degradation of radiolabeled superparamagnetic iron oxide nanoparticles and quantum dots in mice

• Denise Bargheer,
• Artur Giemsa,
• Barbara Freund,
• Markus Heine,
• Christian Waurisch,
• Gordon M. Stachowski,
• Stephen G. Hickey,
• Alexander Eychmüller,
• Jörg Heeren and
• Peter Nielsen

Beilstein J. Nanotechnol. 2015, 6, 111–123, doi:10.3762/bjnano.6.11

• , Germany Institute of Physical Chemistry and Electrochemistry, Technical University of Dresden, Bergstr. 66b, 01069 Dresden, Germany 10.3762/bjnano.6.11 Abstract 51Cr-labeled, superparamagnetic, iron oxide nanoparticles (51Cr-SPIOs) and 65Zn-labeled CdSe/CdS/ZnS-quantum dots (65Zn-Qdots) were prepared

• respective trace element homeostasis, it can also limit the relevance of such trace material-based approaches in nanobioscience. By monitoring 51Cr-SPIOs after oral gavage, the gastrointestinal non-absorption of intact SPIOs in a hydrophilic or lipophilic surrounding was measured in mice with such high

• /CdS/ZnS-Qdots in the liver. Keywords: biodistribution; chromium(III); 51Cr; quantum dots; SPIOs; zinc metabolism; 65Zn; Introduction Quantum dots (Qdots) are semiconductor nanocrystals (2–100 nm in diameter) that combine a strong, size-tunable photoluminescence with robust photostability, which

The fate of a designed protein corona on nanoparticles in vitro and in vivo

• Denise Bargheer,
• Julius Nielsen,
• Gabriella Gébel,
• Markus Heine,
• Sunhild C. Salmen,
• Roland Stauber,
• Horst Weller,
• Joerg Heeren and
• Peter Nielsen

Beilstein J. Nanotechnol. 2015, 6, 36–46, doi:10.3762/bjnano.6.5

• Chemistry, University Hamburg, Grindelallee 117, 20146 Hamburg, Germany Molecular and Cellular Oncology, ENT/University Medical Center Mainz, Langenbeckstr. 1, 55101 Mainz, Germany 10.3762/bjnano.6.5 Abstract A variety of monodisperse superparamagnetic iron oxide particles (SPIOs) was designed in which the

• the binding was substantially diminished without a difference between simply adsorbed and covalently bound protein. However, after incubation with excess albumin and subsequently whole plasma, transferrin from the preformed transferrin corona was more and more lost from SPIOs in the case of adsorbed

• proteins. If non-labeled transferrin was used as preformed corona and excess 125I-labeled albumin was added to the reaction mixtures with different SPIOs, a substantial amount of label was bound to the particles with initially adsorbed transferrin but little or even zero with covalently bound transferrin

The cell-type specific uptake of polymer-coated or micelle-embedded QDs and SPIOs does not provoke an acute pro-inflammatory response in the liver

• Markus Heine,
• Alexander Bartelt,
• Oliver T. Bruns,
• Denise Bargheer,
• Artur Giemsa,
• Barbara Freund,
• Ludger Scheja,
• Christian Waurisch,
• Alexander Eychmüller,
• Rudolph Reimer,
• Horst Weller,
• Peter Nielsen and
• Joerg Heeren

Beilstein J. Nanotechnol. 2014, 5, 1432–1440, doi:10.3762/bjnano.5.155

• employing various cell culture systems described toxic effects of QDs [3][4]. Iron-containing superparamagnetic iron oxide nanocrystals (SPIOs) used for magnetic resonance imaging (MRI) have a relative good reputation given that iron is an essential trace element and it can be assumed that iron from

• degraded SPIOs is transferred to the body iron stores. Nevertheless, iron-induced acute toxic reactions, probably related to the generation of reactive oxygen species, have been described in vitro after uptake of large amount of various SPIOs [5]. However, cell culture studies like the ones described above

• -loaded, parenchymal cells. Thus, there is need for in vivo studies addressing the biological fate of QDs as well as SPIOs with regard to potential harmful effects in whole organisms. Recent research investigating the metabolism and excretion of nanocrystals focuses on exposure routes. The excretion of