Classification and application of metal-based nanoantioxidants in medicine and healthcare

• Nguyen Nhat Nam,
• Nguyen Khoi Song Tran,
• Tan Tai Nguyen,
• Nguyen Ngoc Trai,
• Nguyen Phuong Thuy,
• Hoang Dang Khoa Do,
• Nhu Hoa Thi Tran and
• Kieu The Loan Trinh

Beilstein J. Nanotechnol. 2024, 15, 396–415, doi:10.3762/bjnano.15.36

• the conjugation of gold nanoparticles (AuNPs) with an anti-epithelial sodium channel (ENaC), known as a marker for arterial hypertension found in membrane platelets [186]. Beyond nanotechnology, the field has witnessed developments in metallic biomaterials for vascular tissue engineering. Titanium

• biomaterials for vascular interventions and cardiovascular therapeutics. As researchers continue to discover the intricacies of CVDs, the integration of metal-based materials holds promise for more effective clinical strategies. Challenges of metal-based nanoantioxidants in medicine and healthcare Metal-based

New application of bimetallic Ag/Pt nanoplates in a colorimetric biosensor for specific detection of E. coli in water

• Azam Bagheri Pebdeni,
• Mohammad N. AL-Baiati and
• Morteza Hosseini

Beilstein J. Nanotechnol. 2024, 15, 95–103, doi:10.3762/bjnano.15.9

• Department of Pharmaceutical Biomaterials and Medicinal Biomaterials Research Center,Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran 10.3762/bjnano.15.9 Abstract A fast and sensitive aptasensor was developed using nanoplates with peroxidase activity as a novel approach. E. coli

Determination of the radii of coated and uncoated silicon AFM sharp tips using a height calibration standard grating and a nonlinear regression function

• Perawat Boonpuek and
• Jonathan R. Felts

Beilstein J. Nanotechnol. 2023, 14, 1200–1207, doi:10.3762/bjnano.14.99

• nanostructured materials, for example, graphene, carbon nanotubes, nanoscale semiconductors, biomaterials, and molecules. Mechanical properties such as surface stiffness, adhesion, friction, electrostatics, and electrowetting can be measured [1][2][3][4]. In contact mode scanning, the contact area between the

Hierarchically patterned polyurethane microgrooves featuring nanopillars or nanoholes for neurite elongation and alignment

• Lester Uy Vinzons,
• Guo-Chung Dong and
• Shu-Ping Lin

Beilstein J. Nanotechnol. 2023, 14, 1157–1168, doi:10.3762/bjnano.14.96

• ; Introduction The surface features of biomaterials at the micro- and the nanoscale play a crucial role in modulating tissue responses and in determining the functional and temporal efficacy of implants [1]. Micro- and nanoscale surface structures affect cellular functions through micro- and nanometer-sized cell

• ]. Therefore, there is still a need to develop simple and cost-effective fabrication methods applicable to a wide range of nano- and micropatterns and biomaterials. In our previous studies, we have shown how nanosphere lens lithography (NLL) can be used with a low-cost ultraviolet light-emitting diode (UV-LED

Biomimetics on the micro- and nanoscale – The 25th anniversary of the lotus effect

• Matthias Mail,
• Kerstin Koch,
• Thomas Speck,
• William M. Megill and
• Stanislav N. Gorb

Beilstein J. Nanotechnol. 2023, 14, 850–856, doi:10.3762/bjnano.14.69

• biological processes and surface interactions involved in the bioselective adhesion of mammalian cells. The second topic of the review was on repellence of microbes on protein-based material surfaces, highlighting the importance of materials made of recombinant spider silk proteins. Biomaterials that

Nanostructured lipid carriers containing benznidazole: physicochemical, biopharmaceutical and cellular in vitro studies

• Giuliana Muraca,
• María Esperanza Ruiz,
• Rocío C. Gambaro,
• Sebastián Scioli-Montoto,
• María Laura Sbaraglini,
• Gisel Padula,
• José Sebastián Cisneros,
• Cecilia Yamil Chain,
• Vera A. Álvarez,
• Cristián Huck-Iriart,
• Guillermo R. Castro,
• María Belén Piñero,
• Matias Ildebrando Marchetto,
• Catalina Alba Soto,
• Germán A. Islan and
• Alan Talevi

Beilstein J. Nanotechnol. 2023, 14, 804–818, doi:10.3762/bjnano.14.66

• nanoparticles (ISO/TR 7406 or ASTM E2524-08 standard) established that biomaterials that induce a critical hemolytic ratio of <5% can be considered safe for biological applications [46]. In our study, it was observed no hemolytic effects for BNZ, NLC-VEHICLE, and NLC-BNZ at different concentrations after 3 and

Molecular nanoarchitectonics: unification of nanotechnology and molecular/materials science

• Katsuhiko Ariga

Beilstein J. Nanotechnol. 2023, 14, 434–453, doi:10.3762/bjnano.14.35

• in a designed layered structure. As summarized in the review by Akashi and Akagi, LbL assembly is valuable as a pathway to the design and development of innovative biomaterials for tissue engineering [100]. Interfacial phenomena contribute significantly to material accumulation and property

New trends in nanobiotechnology

• Pau-Loke Show,
• Kit Wayne Chew,
• Wee-Jun Ong,
• Sunita Varjani and
• Joon Ching Juan

Beilstein J. Nanotechnol. 2023, 14, 377–379, doi:10.3762/bjnano.14.32

• nanobiotechnological processes to encourage the development of these converging technologies for a sustainable economic growth. The synthesis and the characterization of nanoscale biomaterials, the innovative applications of “smart nanoparticles”, and the technological/biological impact of nanoscale systems are just

• biocompatibility of the nanomaterials is also discussed. The thematic issue also recorded a work on the topic of “Self-assembly of amino acids toward functional biomaterials” [5], where the role of biomaterials in nanobiotechnology is discussed. In this review, the latest advances in amino acid self-assembly and

Antimicrobial and mechanical properties of functionalized textile by nanoarchitectured photoinduced Ag@polymer coating

• Jessica Plé,
• Marine Dabert,
• Helene Lecoq,
• Sophie Hellé,
• Lydie Ploux and
• Lavinia Balan

Beilstein J. Nanotechnol. 2023, 14, 95–109, doi:10.3762/bjnano.14.11

• Jessica Ple Marine Dabert Helene Lecoq Sophie Helle Lydie Ploux Lavinia Balan Université d’Orléans, Conditions Extrêmes Matériaux Haute Température et Irradiation CNRS UPR 3079, F-45000, Orléans, France Biomaterials Bioengineering INSERM/Université de Strasbourg U1121, Centre de Recherche en

Hydroxyapatite–bioglass nanocomposites: Structural, mechanical, and biological aspects

• Olga Shikimaka,
• Mihaela Bivol,
• Bogdan A. Sava,
• Marius Dumitru,
• Christu Tardei,
• Beatrice G. Sbarcea,
• Daria Grabco,
• Constantin Pyrtsac,
• Daria Topal,
• Andrian Prisacaru,
• Vitalie Cobzac and
• Viorel Nacu

Beilstein J. Nanotechnol. 2022, 13, 1490–1504, doi:10.3762/bjnano.13.123

• development of new synthetic biomaterials that are perfectly compatible with biological tissue and provide special functionalities for healing, regeneration, and substitution of diseased or injured bones, as an alternative to “allograft” and “autograft” transplantology methods, which have a number of

Biomimetic chitosan with biocomposite nanomaterials for bone tissue repair and regeneration

• Se-Kwon Kim,
• Sesha Subramanian Murugan,
• Pandurang Appana Dalavi,
• Sebanti Gupta,
• Sukumaran Anil,
• Gi Hun Seong and
• Jayachandran Venkatesan

Beilstein J. Nanotechnol. 2022, 13, 1051–1067, doi:10.3762/bjnano.13.92

• Se-Kwon Kim Sesha Subramanian Murugan Pandurang Appana Dalavi Sebanti Gupta Sukumaran Anil Gi Hun Seong Jayachandran Venkatesan Department of Marine Science and Convergence Engineering, College of Science and Technology, Hanyang University, Gyeonggi-do 11558, Korea Biomaterials Research Laboratory

• properties to bone graft substitutes. Therefore, to get all the three properties of bone graft substitutes, synthetic biomaterials are often mixed with growth factors and host-derived cells to increase bone formation [3]. Bone tissue engineering is the process of developing bone graft biomaterials with the

• combination of materials, growth factors, and cells [4]. Both natural and synthetic materials have been extensively studied for bone graft substitutes [5][6]. Natural biomaterials often are biocompatible, biodegradable, and less toxic to cells, whereas synthetic biomaterials have excellent mechanical strength

Bioselectivity of silk protein-based materials and their bio-inspired applications

• Hendrik Bargel,
• Vanessa T. Trossmann,
• Christoph Sommer and
• Thomas Scheibel

Beilstein J. Nanotechnol. 2022, 13, 902–921, doi:10.3762/bjnano.13.81

• Hendrik Bargel Vanessa T. Trossmann Christoph Sommer Thomas Scheibel Department of Biomaterials, University of Bayreuth, Prof.-Rüdiger-Bormann-Str. 1, 95447 Bayreuth, Germany Bayreuth Center of Material Science and Engineering (BayMat), University of Bayreuth, Universitätsstr. 30, 95440 Bayreuth

• . Engineering biomaterials that stimulate and interact with cell receptors to support binding and subsequent physiological responses of multicellular systems attracted much interest in the last years. Further to this, the increasing threat of multidrug resistance of pathogens against antibiotics to human health

• of bio-inspired selective surface modifications The increasing knowledge on natural receptor–ligand binding mechanisms led to various approaches in the last years to increase both cellular adhesion on surfaces of biomaterials and biosensors, as well as for therapeutic drug carrier systems against

Micro- and nanotechnology in biomedical engineering for cartilage tissue regeneration in osteoarthritis

• Zahra Nabizadeh,
• Mahmoud Nasrollahzadeh,
• Hamed Daemi,
• Mohamadreza Baghaban Eslaminejad,
• Ali Akbar Shabani,
• Mehdi Dadashpour,
• Majid Mirmohammadkhani and
• Davood Nasrabadi

Beilstein J. Nanotechnol. 2022, 13, 363–389, doi:10.3762/bjnano.13.31

• administration of new and efficient options for treating osteochondral lesions. This paper presents an overview of the recent advances in osteochondral tissue engineering resulting from the application of micro- and nanotechnology approaches in the structure of biomaterials, including biological and microscale

• application of such stimuli pave the way for the application of new and promising sources for re-engineering of biomaterials. In this paper, the native structure of articular cartilage is briefly described due to the importance of understanding its complex structure before designing a suitable construct

• . Afterward, recent advances in osteochondral tissue engineering resulting from the application of microspheres, nanoparticles, nanofibers, and nanotubes in the structure of biomaterials will be covered (Figure 1). Finally, the role of various cues such as biological cues, microscale/nanoscale topographical

Systematic studies into uniform synthetic protein nanoparticles

• Nahal Habibi,
• Ava Mauser,
• Jeffery E. Raymond and
• Joerg Lahann

Beilstein J. Nanotechnol. 2022, 13, 274–283, doi:10.3762/bjnano.13.22

• SPNPs made from blended proteins can serve as a promising drug delivery carrier owing to the ease of production, the composition versatility, and the control over their size, shape and dispersity. Keywords: nanogels; nanomedicine; particle characterization; protein-based biomaterials; Introduction As

Engineered titania nanomaterials in advanced clinical applications

• Padmavati Sahare,
• Paulina Govea Alvarez,
• Juan Manual Sanchez Yanez,
• Gabriel Luna-Bárcenas,
• Samik Chakraborty,
• Sujay Paul and
• Miriam Estevez

Beilstein J. Nanotechnol. 2022, 13, 201–218, doi:10.3762/bjnano.13.15

• , titanium nitride (TiN) coating has been licensed by the FDA to be used in titanium alloy components for enhancing durability and corrosion resistance in surgical steel, orthodontics, hip prostheses, and cardiovascular biomaterials [69]. A titania/glass ceramic (TiGC) scaffold was fabricated and coated with

Effect of lubricants on the rotational transmission between solid-state gears

• Huang-Hsiang Lin,
• Jonathan Heinze,
• Alexander Croy,
• Rafael Gutiérrez and
• Gianaurelio Cuniberti

Beilstein J. Nanotechnol. 2022, 13, 54–62, doi:10.3762/bjnano.13.3

• Huang-Hsiang Lin Jonathan Heinze Alexander Croy Rafael Gutierrez Gianaurelio Cuniberti Institute for Materials Science and Max Bergmann Center of Biomaterials, TU Dresden, Dresden, Germany 10.3762/bjnano.13.3 Abstract Lubricants are widely used in macroscopic mechanical systems to reduce friction

Sputtering onto liquids: a critical review

• Anastasiya Sergievskaya,
• Adrien Chauvin and
• Stephanos Konstantinidis

Beilstein J. Nanotechnol. 2022, 13, 10–53, doi:10.3762/bjnano.13.2

• properties to fit the targeted application in fields such as mechanics, optics, electronics, and biomaterials. Various types of coatings can be produced, from pure metals to metal oxides, nitrides, carbides, oxynitrides to metal alloys, or chemically more complex combinations such as high-entropy alloys [24

Self-assembly of amino acids toward functional biomaterials

• Huan Ren,
• Lifang Wu,
• Lina Tan,
• Yanni Bao,
• Yuchen Ma,
• Yong Jin and
• Qianli Zou

Beilstein J. Nanotechnol. 2021, 12, 1140–1150, doi:10.3762/bjnano.12.85

• biomaterials; intermolecular interactions; self-assembly; Review Introduction Biomaterials play a crucial role in the treatment of diseases and health care and have been widely used in prostheses and drug delivery devices [1]. Clinical applications of biomaterials include the use of metals, ceramics, and

• ]. Although traditional materials provide good structural analogues for native bone and surrounding tissue, they are difficult to mimic the dynamics and complexity of the natural environment [9]. Therefore, it is necessary to develop a new generation of biomaterials to improve strategies for natural tissue

• ions, multi-component collaborative self-assembly) as a general strategy for functional biomaterials research. Summary of amino acids/amino acid derivatives and their applications.

Comprehensive review on ultrasound-responsive theranostic nanomaterials: mechanisms, structures and medical applications

• Sepand Tehrani Fateh,
• Lida Moradi,
• Elmira Kohan,
• Michael R. Hamblin and
• Amin Shiralizadeh Dezfuli

Beilstein J. Nanotechnol. 2021, 12, 808–862, doi:10.3762/bjnano.12.64

• opportunity for the development of new biomaterials. The optimization of their responses to local/environmental stimuli can provide better-controlled drug delivery and superior therapeutic effects through the synergistic effect of various environmental stimuli [8][9]. These systems have been discussed in

Silver nanoparticles induce the cardiomyogenic differentiation of bone marrow derived mesenchymal stem cells via telomere length extension

• Khosro Adibkia,
• Ali Ehsani,
• Asma Jodaei,
• Ezzatollah Fathi,
• Raheleh Farahzadi and
• Mohammad Barzegar-Jalali

Beilstein J. Nanotechnol. 2021, 12, 786–797, doi:10.3762/bjnano.12.62

• attention. Novel nanomaterials are being developed to improve disease treatment processes via biopharmaceutical molecules as well as the surface treatment of biomaterials [8][9]. Among nanoparticles (NPs), silver nanoparticles (Ag-NPs) are successfully commercialized due to their well-known antiseptic

Recent progress in actuation technologies of micro/nanorobots

• Ke Xu and
• Bing Liu

Beilstein J. Nanotechnol. 2021, 12, 756–765, doi:10.3762/bjnano.12.59

• then copper sulfate was added to make the bacterial flagella enter a “paralysis” state. Finally, ethylenediaminetetraacetic acid was used to separate the copper sulfate, so that the bacteria could move again. The success of this research created a theoretical basis for the use of biomaterials for self

Colloidal particle aggregation: mechanism of assembly studied via constructal theory modeling

• Scott C. Bukosky,
• Sukrith Dev,
• Monica S. Allen and
• Jeffery W. Allen

Beilstein J. Nanotechnol. 2021, 12, 413–423, doi:10.3762/bjnano.12.33

• variety of applications, including plasmonic/photonic devices, metamaterials, biomaterials and coatings, energetic materials, and high-strength ceramics [15][16][17][18][19][20][21][22][23][24][25]. Most applications, however, require precise manipulation of the particle placement, spacing, and

Characterization, bio-uptake and toxicity of polymer-coated silver nanoparticles and their interaction with human peripheral blood mononuclear cells

• Sahar Pourhoseini,
• Reilly T. Enos,
• Angela E. Murphy,
• Bo Cai and
• Jamie R. Lead

Beilstein J. Nanotechnol. 2021, 12, 282–294, doi:10.3762/bjnano.12.23

• dermal and ocular contact [18]. As AgNPs enter the body through injection or degradation of biomaterials, they are translocated to the circulatory system and can come in direct contact with human peripheral blood mononuclear cells (PBMCs) before ultimately being distributed to the main organs where they

Fusion of purple membranes triggered by immobilization on carbon nanomembranes

• René Riedel,
• Natalie Frese,
• Fang Yang,
• Martin Wortmann,
• Raphael Dalpke,
• Daniel Rhinow,
• Norbert Hampp and
• Armin Gölzhäuser

Beilstein J. Nanotechnol. 2021, 12, 93–101, doi:10.3762/bjnano.12.8

• Physics, Bielefeld University, Universitätsstraße 25, D-33615 Bielefeld, Germany Nano Biomaterials Group, Ningbo Institute of Industrial Technology, Chinese Academy of Science, China Faculty of Engineering and Mathematics, Bielefeld University of Applied Sciences, Interaktion 1, D-33619 Bielefeld, Germany

Gram-scale synthesis of splat-shaped Ag–TiO₂ nanocomposites for enhanced antimicrobial properties

• Mohammad Jaber,
• Asim Mushtaq,
• Kebiao Zhang,
• Jindan Wu,
• Dandan Luo,
• Zihan Yi,
• M. Zubair Iqbal and
• Xiangdong Kong

Beilstein J. Nanotechnol. 2020, 11, 1119–1125, doi:10.3762/bjnano.11.96

• Zhejiang-Mauritius Joint Research Center for Biomaterials and Tissue Engineering, Hangzhou 310018, China 10.3762/bjnano.11.96 Abstract The control over contagious diseases caused by pathogenic organisms has become a serious health issue. The extensive usage of antibiotics has led to the development of

• . The improvement in the antibacterial activity was attributed to the synergistic effect of the hybrid nature of TiO2 nanoparticles in the presence of Ag. Keywords: antimicrobial properties; biomaterials; nanocomposites; silver nanoparticles; titanium dioxide; Introduction The rapid industrial