Fabrication and characterization of novel multilayered structures by stereocomplexion of poly(D-lactic acid)/poly(L-lactic acid) and self-assembly of polyelectrolytes

• Elena Dellacasa,
• Li Zhao,
• Gesheng Yang,
• Laura Pastorino and
• Gleb B. Sukhorukov

Beilstein J. Nanotechnol. 2016, 7, 81–90, doi:10.3762/bjnano.7.10

• between the (PDLA/PLLA)n stereocomplex and the cores with and without the polymeric (PSS/PAH)n/PLL multilayer precursor (PEM). Nuclear magnetic resonance (NMR) and gel permeation chromatography (GPC) were used to characterize the chemical composition and molecular weight of poly(lactic acid) polymers

• for sustained release. Keywords: biocompatibility; layer-by-layer assembly; microcapsules; poly(lactic acids); stereocomplex; Introduction The polycationic/polyanionic layer-by-layer (LBL) deposition on surfaces has been widely studied since the first description by Decher et al. [1][2][3]. The

• ) and poly(D-lactic acid) (PDLA) enantiomers, forming a racemic crystal called a stereocomplex, has been successfully realized [35]. However, PLA capsules made by the LBL technique with an entirely biocompatible procedure remain a challenge [36][37][38]. The possibility to assemble these polymers, as