An improved synthesis of 1,3,5-triaryl-2-pyrazolines in acetic acid aqueous solution under ultrasound irradiation

Ji-Tai Li, Xiao-Hui Zhang and Zhi-Ping Lin
Beilstein J. Org. Chem. 2007, 3, No. 13. https://doi.org/10.1186/1860-5397-3-13

Supporting Information

Supporting Information File 1: Experimental Section. Experimental detail data which includes experimental detail of the spectral instruments, synthesis of 1,3,5-triaryl-2-pyrazolines,1H NMR, 13C, IR and elemental analysis data along with ultrasonic instrument.
Format: DOC Size: 41.5 KB Download

Cite the Following Article

An improved synthesis of 1,3,5-triaryl-2-pyrazolines in acetic acid aqueous solution under ultrasound irradiation
Ji-Tai Li, Xiao-Hui Zhang and Zhi-Ping Lin
Beilstein J. Org. Chem. 2007, 3, No. 13. https://doi.org/10.1186/1860-5397-3-13

How to Cite

Li, J.-T.; Zhang, X.-H.; Lin, Z.-P. Beilstein J. Org. Chem. 2007, 3, No. 13. doi:10.1186/1860-5397-3-13

Download Citation

Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window below.
Citation data in RIS format can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Zotero.

Citations to This Article

Up to 20 of the most recent references are displayed here.

Scholarly Works

  • Ray, P. K.; Salahuddin; Mazumder, A.; Kumar, R.; Ahsan, M. J.; Yar, M. S. Synthetic Strategies of Pyrazoline Derivatives for the Development of New Anticancer Agents: Recent Updates. Mini-Reviews in Organic Chemistry 2024, 21, 92–132. doi:10.2174/1570193x19666220324125350
  • de Farias, I. F.; Gonçalves, R. d. O.; de Freitas, M. D.; da Silva, F. L.; de Sousa, A. F.; Trevisan, M. T. S.; Lomonaco, D.; Monte, F. J. Q.; da Fonseca, A. M.; de Lemos, T. L. G. Synthesis, characterization and molecular docking study of pyrazolines synthesized from chalcones: Antioxidant and acetylcholinesterase activities. Journal of Molecular Structure 2023, 1291, 135961. doi:10.1016/j.molstruc.2023.135961
  • Isakhanyan, A. U.; Hakobyan, N. Z.; Hovasyan, Z. A.; Grigoryan, G. S.; Mkhitaryan, R. P.; Aracelyan, H. G.; Safaryan, A. S.; Muradyan, R. E.; Panosyan, Н. A.; Harutyunyan, A. A. Synthesis, Luminescent Properties, and Antibacterial Activity of New Pyrazoline and Pyrimidine Derivatives of (2E)-1-Biphenyl-3-arylprop-2-en-1-ones. Russian Journal of General Chemistry 2023, 93, 2210–2216. doi:10.1134/s1070363223090037
  • Kumar, R.; Singh, H.; Mazumder, A.; Salahuddin; Yadav, R. K. Synthetic Approaches, Biological Activities, and Structure-Activity Relationship of Pyrazolines and Related Derivatives. Topics in current chemistry (Cham) 2023, 381, 12. doi:10.1007/s41061-023-00422-z
  • Kumar, R.; Singh, H.; Mazumder, A.; Salahuddin; Yadav, R. K. Current Developments in Synthetic Protocols for Pyrazolines and Analogs. Current Organic Chemistry 2023, 27, 710–726. doi:10.2174/1385272827666230731091839
  • Ghorbani, P.; Nasr-Esfahani, M.; Eftekhari Far, B. Synthesis of Chalcones and Pyrazolines Using NB-Fe3O4@SiO2@CPTMO@DEA-SO3H as an Efficient and Reusable Nanocatalyst. Russian Journal of Organic Chemistry 2022, 58, 1812–1820. doi:10.1134/s1070428022120107
  • Ratnani, S.; Mahilkar Sonkar, S.; Kumari, R. Strategies for sustainable organic synthesis. Journal of the Iranian Chemical Society 2022, 20, 495–508. doi:10.1007/s13738-022-02687-5
  • Morsy, N. M.; Hassan, A. S. Synthesis, reactions, and applications of chalcones: A review. European Journal of Chemistry 2022, 13, 241–252. doi:10.5155/eurjchem.13.2.241-252.2245
  • Sabah, R. S.; Al-Garawi, Z. S.; Al-jibouri, M. N. The utilities of pyrazolines encouraged synthesis of a new pyrazoline derivative via ring closure of chalcone, for optimistic neurodegenerative applications. Al-Mustansiriyah Journal of Science 2022, 33, 21–31. doi:10.23851/mjs.v33i1.1067
  • Priyanka, P.; Sivapriya, S.; Gopalakrishnan, M.; Pazhamalai, S.; Seenivasan, M.; Manikandan, H. Synthesis, Characterization and DFT Calculations of a Novel Pyrazole Derivative 4-(1-Phenyl-5-(p-Tolyl)-2,5-Dihydro-1H-Pyrazol-3-Yl)Benzo[c][1,2,5]Oxadiazole. Materials Science Forum 2022, 1048, 227–238. doi:10.4028/www.scientific.net/msf.1048.227
  • Queiroz, J. E.; Dias, L. D.; Verde, G. M. V.; Aquino, G. L.; Camargo, A. J. An Update on the Synthesis and Pharmacological Properties of Pyrazoles Obtained from Chalcone. Current Organic Chemistry 2022, 26, 81–90. doi:10.2174/1385272826666220119110347
  • Kumar Jain, S.; Singhal, R.; K. Jain, N. Synthesis, characterization and biological activity of Pyrazoline derivatives. Research Journal of Pharmacy and Technology 2021, 6223–6227. doi:10.52711/0974-360x.2021.01077
  • Vahedpour, T.; Hamzeh-Mivehroud, M.; Hemmati, S.; Dastmalchi, S. Synthesis of 2-Pyrazolines from Hydrazines: Mechanisms Explained. ChemistrySelect 2021, 6, 6483–6506. doi:10.1002/slct.202101467
  • Farooq, S.; Ngaini, Z.; Daud, A. I.; Khairul, W. M. Microwave Assisted Synthesis and Antimicrobial Activities of Carboxylpyrazoline Derivatives: Molecular Docking and DFT Influence in Bioisosteric Replacement. Polycyclic Aromatic Compounds 2021, 1–14.
  • Sameri, F.; Bodaghifard, M. A.; Mobinikhaledi, A. Ionic Liquid-Coated Nanoparticles (CaO@SiO2@BAIL): A Bi-Functional and Environmentally Benign Catalyst for Green Synthesis of Pyridine, Pyrimidine, and Pyrazoline Derivatives. Polycyclic Aromatic Compounds 2021, 1–17.
  • Mukherjee, N.; Maity, P.; Ranu, B. C. Use of ball milling for the synthesis of biologically active heterocycles. Green Synthetic Approaches for Biologically Relevant Heterocycles; Elsevier, 2021; pp 167–187. doi:10.1016/b978-0-12-820586-0.00007-8
  • Puri, S.; Parmar, A.; Chopra, H. K. Ultrasound assisted reactions. Handbook of Greener Synthesis of Nanomaterials and Compounds; Elsevier, 2021; pp 177–246. doi:10.1016/b978-0-12-821938-6.00006-2
  • Navdeep, S.; Monika, G. Therapeutic Journey of Pyrazolines as EGFR Tyrosine Kinase Inhibitors: An Insight into Structure-Activity Relationship. Current Bioactive Compounds 2020, 16, 1260–1272. doi:10.2174/1573407216666200128155640
  • Al-Saheb, R.; Makharza, S. A.; Al-Battah, F.; Abu-El-Halawa, R.; Kaimari, T.; Abu Abed, O. S. Synthesis of new pyrazolone and pyrazole-based adamantyl chalcones and antimicrobial activity. Bioscience reports 2020, 40. doi:10.1042/bsr20201950
  • Behrouz, S.; Rad, M. N. S.; Abdollahzadeh, M.; Piltan, M. A. Ultrasound-Promoted Mild, and Efficient Protocol for Three-Component Synthesis of 2,4,5-Trisubstituted Imidazoles Using Urea and PPh3 as the Sources of Nitrogen and Organocatalyst. ChemistrySelect 2020, 5, 7467–7473. doi:10.1002/slct.202001722
Other Beilstein-Institut Open Science Activities