Chemo-enzymatic modification of poly-N-acetyllactosamine (LacNAc) oligomers and N,N-diacetyllactosamine (LacDiNAc) based on galactose oxidase treatment

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• Chen, C.-Y.; Lin, Y.-W.; Wang, S.-W.; Lin, Y.-C.; Cheng, Y.-Y.; Ren, C.-T.; Wong, C.-H.; Wu, C.-Y. Synthesis of Azido-Globo H Analogs for Immunogenicity Evaluation. ACS central science 2021, 8, 77–85. doi:10.1021/acscentsci.1c01277
• Ziganshina, M. M.; Dolgushina, N. V.; Kulikova, G. V.; Fayzullina, N. M.; Yarotskaya, E.; Khasbiullina, N. R.; Abdurakhmanova, N. F.; Asaturova, A. V.; Shchegolev, A. I.; Dovgan, A. A.; Sukhikh, G. T. Epithelial apical glycosylation changes associated with thin endometrium in women with infertility - a pilot observational study. Reproductive biology and endocrinology : RB&E 2021, 19, 73. doi:10.1186/s12958-021-00750-z
• Dussouy, C.; Téletchéa, S.; Lambert, A.; Charlier, C.; Botez, I.; De Ceuninck, F.; Grandjean, C. Access to Galectin-3 Inhibitors from Chemoenzymatic Synthons. The Journal of organic chemistry 2020, 85, 16099–16114. doi:10.1021/acs.joc.0c01927
• Wang, Q.; Wang, T.; Yang, S.; Sha, S.; Wu, W. W.; Chen, Y.; Paul, J. T.; Shen, R.-F.; Cipollo, J. F.; Betenbaugh, M. J. Metabolic engineering challenges of extending N-glycan pathways in Chinese hamster ovary cells. Metabolic engineering 2020, 61, 301–314. doi:10.1016/j.ymben.2020.06.007
• Storozhylova, N.; Crecente-Campo, J.; Cabaleiro, D.; Lugo, L.; Dussouy, C.; Simões, S.; Monteiro, M.; Grandjean, C.; Alonso, M. J. An In Situ Hyaluronic Acid-Fibrin Hydrogel Containing Drug-Loaded Nanocapsules for Intra-Articular Treatment of Inflammatory Joint Diseases. Regenerative Engineering and Translational Medicine 2020, 6, 201–216. doi:10.1007/s40883-020-00154-2
• Cosgrove, S. C.; Mattey, A. P.; Riese, M.; Chapman, M. R.; Birmingham, W. R.; Blacker, A. J.; Kapur, N.; Turner, N. J.; Flitsch, S. L. Biocatalytic Oxidation in Continuous Flow for the Generation of Carbohydrate Dialdehydes. ACS Catalysis 2019, 9, 11658–11662. doi:10.1021/acscatal.9b04819
• Lu, N.; Ye, J.; Cheng, J.; Sasmal, A.; Liu, C.-C.; Yao, W.; Yan, J.; Khan, N.; Yi, W.; Varki, A.; Cao, H. Redox-Controlled Site-Specific α2–6-Sialylation. Journal of the American Chemical Society 2019, 141, 4547–4552. doi:10.1021/jacs.9b00044
• Laaf, D.; Bojarová, P.; Elling, L.; Křen, V. Galectin-Carbohydrate Interactions in Biomedicine and Biotechnology. Trends in biotechnology 2018, 37, 402–415. doi:10.1016/j.tibtech.2018.10.001
• Bumba, L.; Laaf, D.; Spiwok, V.; Elling, L.; Křen, V.; Bojarová, P. Poly-N-Acetyllactosamine Neo-Glycoproteins as Nanomolar Ligands of Human Galectin-3: Binding Kinetics and Modeling. International journal of molecular sciences 2018, 19, 372. doi:10.3390/ijms19020372
• Huang, K.; Parmeggiani, F.; Pallister, E.; Huang, C.-J.; Liu, F.-F.; Li, Q.; Birmingham, W. R.; Both, P.; Thomas, B.; Liu, L.; Voglmeir, J.; Flitsch, S. L. Characterisation of a Bacterial Galactokinase with High Activity and Broad Substrate Tolerance for Chemoenzymatic Synthesis of 6-Aminogalactose-1-Phosphate and Analogues. Chembiochem : a European journal of chemical biology 2018, 19, 388–394. doi:10.1002/cbic.201700477
• Laaf, D.; Steffens, H.; Pelantová, H.; Bojarová, P.; Křen, V.; Elling, L. Chemo-Enzymatic Synthesis of Branched N -Acetyllactosamine Glycan Oligomers for Galectin-3 Inhibition. Advanced Synthesis & Catalysis 2017, 359, 4015–4024. doi:10.1002/adsc.201700969
• Laaf, D.; Bojarová, P.; Pelantová, H.; Křen, V.; Elling, L. Tailored Multivalent Neo-Glycoproteins: Synthesis, Evaluation, and Application of a Library of Galectin-3-Binding Glycan Ligands. Bioconjugate chemistry 2017, 28, 2832–2840. doi:10.1021/acs.bioconjchem.7b00520
• Böcker, S.; Elling, L. Biotinylated N-Acetyllactosamine- and N,N-Diacetyllactosamine-Based Oligosaccharides as Novel Ligands for Human Galectin-3. Bioengineering 2017, 4, 31. doi:10.3390/bioengineering4020031
• Böcker, S.; Elling, L. Biotinylated N-Acetyllactosamine- and N,N-Diacetyllactosamine-Based Oligosaccharides as Novel Ligands for Human Galectin-3. Bioengineering (Basel, Switzerland) 2017, 4, 31.
• Wahl, C.; Hirtz, D.; Elling, L. Multiplexed capillary electrophoresis as analytical tool for fast optimization of multi-enzyme cascade reactions synthesis of nucleotide sugars. Biotechnology journal 2016, 11, 1298–1308. doi:10.1002/biot.201600265
• Rosencrantz, R. R.; Nguyen, V. H.; Park, H.; Schulte, C.; Böker, A.; Schnakenberg, U.; Elling, L. Lectin binding studies on a glycopolymer brush flow-through biosensor by localized surface plasmon resonance. Analytical and bioanalytical chemistry 2016, 408, 5633–5640. doi:10.1007/s00216-016-9667-9
• Lange, B.; Simonova, A.; Fischöder, T.; Pelantová, H.; Křen, V.; Elling, L. Towards Keratan Sulfate – Chemoenzymatic Cascade Synthesis of Sulfated N‐Acetyllactosamine (LacNAc) Glycan Oligomers. Advanced Synthesis & Catalysis 2016, 358, 584–596. doi:10.1002/adsc.201500916
• Parikka, K.; Master, E. R.; Tenkanen, M. Oxidation with galactose oxidase: Multifunctional enzymatic catalysis. Journal of Molecular Catalysis B: Enzymatic 2015, 120, 47–59. doi:10.1016/j.molcatb.2015.06.006

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