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Chemical biology

Editor: Prof. Helge B. Bode
Johann-Wolfgang Goethe Universität Frankfurt

This Thematic Series highlights the latest research in chemical biology.

Further articles will follow soon.


A detailed view on 1,8-cineol biosynthesis by Streptomyces clavuligerus

Jan Rinkel, Patrick Rabe, Laura zur Horst, Jeroen S. Dickschat

Beilstein J. Org. Chem. 2016, 12, 2317–2324. published 04 Nov 2016

Full Research Paper

Computational methods in drug discovery

Sumudu P. Leelananda, Steffen Lindert

Beilstein J. Org. Chem. 2016, 12, 2694–2718. published 12 Dec 2016


A non-canonical peptide synthetase adenylates 3-methyl-2-oxovaleric acid for auriculamide biosynthesis

Daniel Braga, Dirk Hoffmeister, Markus Nett

Beilstein J. Org. Chem. 2016, 12, 2766–2770. published 16 Dec 2016


Chemical probes for competitive profiling of the quorum sensing signal synthase PqsD of Pseudomonas aeruginosa

Michaela Prothiwa, Dávid Szamosvári, Sandra Glasmacher, Thomas Böttcher

Beilstein J. Org. Chem. 2016, 12, 2784–2792. published 20 Dec 2016

Full Research Paper

Biochemical and structural characterisation of the second oxidative crosslinking step during the biosynthesis of the glycopeptide antibiotic A47934

Veronika Ulrich, Clara Brieke, Max J. Cryle

Beilstein J. Org. Chem. 2016, 12, 2849–2864. published 27 Dec 2016

Full Research Paper

A postsynthetically 2’-“clickable” uridine with arabino configuration and its application for fluorescent labeling and imaging of DNA

Heidi-Kristin Walter, Bettina Olshausen, Ute Schepers, Hans-Achim Wagenknecht

Beilstein J. Org. Chem. 2017, 13, 127–137. published 20 Jan 2017

Full Research Paper

Versatile synthesis of the signaling peptide glorin

Robert Barnett, Daniel Raszkowski, Thomas Winckler, Pierre Stallforth

Beilstein J. Org. Chem. 2017, 13, 247–250. published 08 Feb 2017

Full Research Paper

Revaluation of biomass-derived furfuryl alcohol derivatives for the synthesis of carbocyclic nucleoside phosphonate analogues

Bemba Sidi Mohamed, Christian Périgaud, Christophe Mathé

Beilstein J. Org. Chem. 2017, 13, 251–256. published 09 Feb 2017

Full Research Paper