Beilstein J. Org. Chem.2016,12, 674–683, doi:10.3762/bjoc.12.68
Vas. Sofias Ave, 11521 Athens, Greece Integrated Center for Childhood Onco-Hematological Investigation, State University of Campinas, P.O. Box 6141, 13083-970 Campinas, SP, Brazil 10.3762/bjoc.12.68 Abstract Jungia sellowii (Asteraceae) is a shrub that grows in Southern Brazil and polar extract of
its leaves presents anti-inflammatory properties. Cyperane, guaiane, nortrixane, and trixane sesquiterpene types were reported as the main metabolites in Jungia species. This work aims to describe the isolation and identification of sesquiterpenes in the leaves of J. sellowii using liquid–liquid
antiprotozoal activity. Liquid–liquid partition and CPC turned to be a versatile technique of glycoside purification which is environmentally friendly and requires a limited amount of organic solvents.
Keywords: CPC; guaiane; Jungia; trixanolide; Introduction
Jungia (Asteraceae) comprises shrubs, lianas and
PDF
Graphical Abstract
Figure 1:
UPLC profile of the butanol fraction of the leaves of Jungia sellowii after shaking the flask with ...