Beilstein J. Org. Chem.2016,12, 969–984, doi:10.3762/bjoc.12.96
-date-explored members of these halophilic or halotolerant myxobacteria are all grouped into the suborder Nannocystineae. Few of them were chemically investigated revealing around 11 structural types belonging to the polyketide, non-ribosomal peptide, hybrids thereof or terpenoid class of secondary
metabolites. A most unusual structural type is represented by salimabromide from Enhygromyxa salina. In silico analyses were carried out on the available genome sequences of four bacterial members of the Nannocystineae, revealing the biosynthetic potential of these bacteria.
Keywords: Enhygromyxa; genome
mining; myxobacteria; Nannocystineae; natural products; Review
Taxonomy and ecology of myxobacteria
Bacteria from the order Myxococcales, commonly known as myxobacteria, are Gram-negative, rod-shaped δ-proteobacteria, comprising compared to many other bacteria large genomes. The 14,782,125 bp large
PDF
Graphical Abstract
Figure 1:
Structures of cystobactamids 507, 919-1 and 919-2.