Beilstein J. Org. Chem.2014,10, 2071–2076, doi:10.3762/bjoc.10.215
products are produced with good enantioselectivity.
Keywords: chiral synthesis; Pd-catalysis; organophosphorus; phosphorus ligands; P(O)R2-directing; Introduction
In the past decades, phosphorus ligands have been demonstrated to be efficient ligands in many metal-catalyzed organic reactions [1][2][3][4
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Graphical Abstract
Scheme 1:
C–H functionalization of P(O)R2 directed through a seven-membered cyclopalladium transition state.