Preparation of pyridine-3,4-diols, their crystal packing and their use as precursors for palladium-catalyzed cross-coupling reactions

• Tilman Lechel,
• Irene Brüdgam and
• Hans-Ulrich Reissig

Beilstein J. Org. Chem. 2010, 6, No. 42, doi:10.3762/bjoc.6.42

• palladium-catalyzed coupling reactions. Fluorescence measurements of the biscoupled products showed a maximum of emission in the violet region of the spectrum. Keywords: bisnonaflates; fluorescence; palladium catalysis; pyridine-3,4-diols; pyridines; Introduction Pyridine scaffolds have been found in

• bistriflates or bisnonaflates 3a–d as the only products in moderate to very good yields (47–90%). A direct comparison showed that the treatment of 2c with Tf2O led to a higher yield than that with Nf2O. This may be due to lower steric hindrance in the case of the triflating reagent. As typical examples of