Efficient synthesis of aziridinecyclooctanediol and 3-aminocyclooctanetriol

• Emine Salamci and
• Ayse Kilic Lafzi

Beilstein J. Org. Chem. 2022, 18, 1539–1543, doi:10.3762/bjoc.18.163

• methods are available for the synthesis of eight-membered [18][19][20][21][22][23][24][25][26][27][28][29] aminocyclitols. On the other hand, the synthesis of a C8-cyclitol derivative containing the aziridine ring has not yet been reported. Therefore, in our continued efforts for efficient syntheses of

Stereoselective syntheses of 3-aminocyclooctanetriols and halocyclooctanetriols

• Emine Salamci and
• Yunus Zozik

Beilstein J. Org. Chem. 2021, 17, 705–710, doi:10.3762/bjoc.17.59

• are also cyclitol derivatives, in which one of the hydroxy groups is replaced by a halogen. They have also attracted interest in the last decade because of their biological activities [11][19]. For instance, some brominated quercitol (cyclohexanepentol) derivatives and bromoconduritol-B act as strong

Regio- and stereoselective synthesis of new diaminocyclopentanols

• Evgeni A. Larin,
• Valeri S. Kochubei and
• Yuri M. Atroshchenko

Beilstein J. Org. Chem. 2014, 10, 2513–2520, doi:10.3762/bjoc.10.262

• with hydrogen bond donors [25]. Additionally, the synthesis of aminocyclitols from cyclitol epoxides has been described [26][27]. It has been shown that the reaction of cyclitol epoxides with nitrogen-containing nucleophiles in the presence of Lewis acids gave a mixture of C1 and C2 adducts. Both

Synthesis and biological evaluation of nojirimycin- and pyrrolidine-based trehalase inhibitors

• Davide Bini,
• Francesca Cardona,
• Matilde Forcella,
• Camilla Parmeggiani,
• Paolo Parenti,
• Francesco Nicotra and
• Laura Cipolla

Beilstein J. Org. Chem. 2012, 8, 514–521, doi:10.3762/bjoc.8.58

• , which ensures the synergistic interactions of an aminocyclitol or a nitrogen-containing heterocycle with the catalytic site, and of a sugar or cyclitol unit with the recognition site. However, this work may highlight relevant structural features of the catalytic site that can give access to specific

Design and synthesis of a cyclitol-derived scaffold with axial pyridyl appendages and its encapsulation of the silver(I) cation

• Pierre-Marc Léo,
• Christophe Morin and
• Christian Philouze

Beilstein J. Org. Chem. 2010, 6, 1022–1024, doi:10.3762/bjoc.6.115

• scaffold with C3v symmetry bearing three axial pyridyl appendages is presented. This pre-organized hexadentate ligand allows complexation of silver(I). The crystal structure of the complex was established. Keywords: cyclitol; glyco-scaffolds; hexadentate; scyllo-inositol; silver(I) complexation

• this work the synthesis of an cyclitol-derived scaffold designed to sequester Ag is presented. Interaction of myo-inositol-derived podands [6] and crown ethers [7] with Ag salts has been shown to depend on the relative spatial orientation of the binding sites moreover, in mono-orthoesters of scyllo