Phosphinate-containing heterocycles: A mini-review

• Olivier Berger and
• Jean-Luc Montchamp

Beilstein J. Org. Chem. 2014, 10, 732–740, doi:10.3762/bjoc.10.67

• rare. The growing availability of synthetic methods will undoubtedly change this situation in the near future. Keywords: amino acid; heterocyle; organophosphorus; phosphinic; phosphorus; Introduction The preparation of P-heterocycles has been the subject of many studies over the years, and the field

Synthesis of chiral N-phosphinyl α-imino esters and their application in asymmetric synthesis of α-amino esters by reduction

• Yiwen Xiong,
• Haibo Mei,
• Lingmin Wu,
• Jianlin Han,
• Yi Pan and
• Guigen Li

Beilstein J. Org. Chem. 2014, 10, 653–659, doi:10.3762/bjoc.10.57

• fragments constituting peptides and proteins, especially for human insulin [24][25][26][27][28]. One of the most straightforward methods to prepare α-amino esters is the direct reduction of α-imino esters [29][30]. Several heterocyle-based reduction reagents have been developed for this transformation in