Discrimination of β-cyclodextrin/hazelnut (Corylus avellana L.) oil/flavonoid glycoside and flavonolignan ternary complexes by Fourier-transform infrared spectroscopy coupled with principal component analysis

• Nicoleta G. Hădărugă,
• Gabriela Popescu,
• Dina Gligor (Pane),
• Cristina L. Mitroi,
• Sorin M. Stanciu and
• Daniel Ioan Hădărugă

Beilstein J. Org. Chem. 2023, 19, 380–398, doi:10.3762/bjoc.19.30

• apparent water solubility and bioaccessibility of the oil and fat components. The oxidative stability of the polyunsaturated FA glycerides or free FAs is significantly increased by CD nanoencapsulation. Thus, a high thermal stability was obtained for linoleic acid encapsulated into α-CD by co

• -crystallization [10]. Omega-3 FA glycerides such as eicosapentaenoic and docosahexaenoic acid glycerides (EPA and DHA glycerides) from fish oil are less stable against oxidation. Their thermal and oxidative stabilities were significantly increased by CD nanoencapsulation as was shown for fish oil from common

• essential oils. Essential oil components are also compatible guests for CD nanoencapsulation. They were studied as “pure” compounds or as essential oil mixtures (e.g., linalool, nerolidol, nootkatone, or sweet basil – Ocimum basilicum L., caraway – Carum carvi L., coriander – Coriandrum sativum L., fennel

The effect of cyclodextrin complexation on the solubility and photostability of nerolidol as pure compound and as main constituent of cabreuva essential oil

• Joyce Azzi,
• Pierre-Edouard Danjou,
• David Landy,
• Steven Ruellan,
• Lizette Auezova,
• Hélène Greige-Gerges and
• Sophie Fourmentin

Beilstein J. Org. Chem. 2017, 13, 835–844, doi:10.3762/bjoc.13.84

• this goal, Ner should be dissolved partially or totally in aqueous media to provide an efficient interaction with the pathogens [5]. However, Ner is poorly soluble in water and is also subject to degradation during storage. Nanoencapsulation techniques may improve Ner solubility and stability allowing

Thermal and oxidative stability of Atlantic salmon oil (Salmo salar L.) and complexation with β-cyclodextrin

• Daniel I. Hădărugă,
• Mustafa Ünlüsayin,
• Alexandra T. Gruia,
• Cristina Birău (Mitroi),
• Gerlinde Rusu and
• Nicoleta G. Hădărugă

Beilstein J. Org. Chem. 2016, 12, 179–191, doi:10.3762/bjoc.12.20

• -containing microcapsules [27][33] and spontaneous emulsification for obtaining nanoemulsions [20][31][32]. One nanoencapsulation method of fish oil components is the molecular encapsulation in cyclodextrins (CDs). The latter are natural or synthetically modified, cyclic oligosaccharides comprising 6, 7, and

Thermal and oxidative stability of the Ocimum basilicum L. essential oil/β-cyclodextrin supramolecular system

• Daniel I. Hădărugă,
• Nicoleta G. Hădărugă,
• Corina I. Costescu,
• Ioan David and
• Alexandra T. Gruia

Beilstein J. Org. Chem. 2014, 10, 2809–2820, doi:10.3762/bjoc.10.298

• . essential oil in comparison with the corresponding β-CD complex. For the first time, the protective capability of natural β-CD for labile basil essential oil compounds has been demonstrated. Keywords: basil; β-cyclodextrin; GC–MS analysis; nanoencapsulation; Ocimum basilicum L. essential oil; thermal and

• nanoencapsulation in CDs from both a geometrical and a hydrophobic point of view. The essential oil components (including basil essential oil), such as pinenes, linalool, terpineol and phenol derivatives can be appropriately nanoencapsulated in CDs due to their structural and hydrophobic characteristics [39][40][41

• competitivity in the molecular encapsulation process. The competition for nanoencapsulation of O. basilicum L. essential oil constituents in β-CD is better assessed by using multivariate statistical analysis (PCA) for both the encapsulation data and the structural descriptors. All essential oil compounds were