Synthesis of imidazo[4,5-e][1,3]thiazino[2,3-c][1,2,4]triazines via a base-induced rearrangement of functionalized imidazo[4,5-e]thiazolo[2,3-c][1,2,4]triazines

• Dmitry B. Vinogradov,
• Alexei N. Izmest’ev,
• Angelina N. Kravchenko,
• Yuri A. Strelenko and
• Galina A. Gazieva

Beilstein J. Org. Chem. 2023, 19, 1047–1054, doi:10.3762/bjoc.19.80

• (PD404182) [1][2][3][4], sedative [5] and antitumor agents [6][7][8], as well as fungicides [9][10] and insecticides [11] have been found (Figure 1). The 1,3-thiazine heterocyclic system is comprised in some natural phytoalexins (cyclobrassinin, sinalbins A and B, rutalexin, and others) [12] and 7

Phytoalexins of the Pyrinae: Biphenyls and dibenzofurans

• Cornelia Chizzali and
• Ludger Beerhues

Beilstein J. Org. Chem. 2012, 8, 613–620, doi:10.3762/bjoc.8.68

• Cornelia Chizzali Ludger Beerhues Institut für Pharmazeutische Biologie, Technische Universität Braunschweig, Mendelssohnstr. 1, 38106 Braunschweig, Germany 10.3762/bjoc.8.68 Abstract Biphenyls and dibenzofurans are the phytoalexins of the Pyrinae, a subtribe of the plant family Rosaceae. The

• after treatment with biotic and abiotic elicitors. The antimicrobial activity of the phytoalexins was demonstrated. To date, 10 biphenyls and 17 dibenzofurans were isolated from 14 of the 30 Pyrinae genera. The most widely distributed compounds are the biphenyl aucuparin and the dibenzofuran γ

• by a gene family, members of which are differentially regulated. Metabolism of the phytoalexins may provide new tools for designing disease control strategies for fruit trees of the Pyrinae subtribe. Keywords: biphenyls; dibenzofurans; phytoalexins; Pyrinae; Sorbus aucuparia; Review Diversity of