Organofluorine chemistry VI

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Editor: Prof. David O'Hagan
University of St Andrews
 
It is a pleasure to launch the 6th Thematic Issue on organofluorine chemistry in the Beilstein Journal of Organic Chemistry. The special characteristics of fluorine, which stem from its high electronegativity and its ability to form stable bonds to carbon, render it particularly useful in optimising the properties of molecules in all areas where organic chemicals are applied. Thus, organofluorine compounds emerge prominently in the pharmaceutical and agrochemicals industries, and they have had a long history in the development of polymers and more recently in soft materials, such as those associated with modern display technologies. Some structural classes, such as perfluorochemicals, are presenting challenges due to their environmental impact. Therefore, it is now necessary that such considerations are incorporated into innovations in the development of functional molecules containing fluorine. New synthetic methods for selective fluorinations and understanding the properties and life cycle of fluorine-containing compounds provide the stimulus now for innovation in organofluorine chemistry.  It is in that context that BJOC continues its commitment to this subdiscipline of organic chemistry by opening the 6th Thematic Issue on organofluorine chemistry. Contributions from academic and industrial laboratories across all areas of the organofluorine enterprise are welcome.

David O'Hagan, University of St Andrews
Guest Editor of Organofluorine chemistry VI

Submission deadline: July 31, 2024
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Visible-light-induced nickel-catalyzed α-hydroxytrifluoroethylation of alkyl carboxylic acids: Access to trifluoromethyl alkyl acyloins

  • Feng Chen,
  • Xiu-Hua Xu,
  • Zeng-Hao Chen,
  • Yue Chen and
  • Feng-Ling Qing

Beilstein J. Org. Chem. 2023, 19, 1372–1378, doi:10.3762/bjoc.19.98

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Published 11 Sep 2023

Morpholine-mediated defluorinative cycloaddition of gem-difluoroalkenes and organic azides

  • Tzu-Yu Huang,
  • Mario Djugovski,
  • Sweta Adhikari,
  • Destinee L. Manning and
  • Sudeshna Roy

Beilstein J. Org. Chem. 2023, 19, 1545–1554, doi:10.3762/bjoc.19.111

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Letter
Published 05 Oct 2023

Trifluoromethylated hydrazones and acylhydrazones as potent nitrogen-containing fluorinated building blocks

  • Zhang Dongxu

Beilstein J. Org. Chem. 2023, 19, 1741–1754, doi:10.3762/bjoc.19.127

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Review
Published 15 Nov 2023

Copper-catalyzed multicomponent reaction of β-trifluoromethyl β-diazo esters enabling the synthesis of β-trifluoromethyl N,N-diacyl-β-amino esters

  • Youlong Du,
  • Haibo Mei,
  • Ata Makarem,
  • Ramin Javahershenas,
  • Vadim A. Soloshonok and
  • Jianlin Han

Beilstein J. Org. Chem. 2024, 20, 212–219, doi:10.3762/bjoc.20.21

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Published 02 Feb 2024

(E,Z)-1,1,1,4,4,4-Hexafluorobut-2-enes: hydrofluoroolefins halogenation/dehydrohalogenation cascade to reach new fluorinated allene

  • Nataliia V. Kirij,
  • Andrey A. Filatov,
  • Yurii L. Yagupolskii,
  • Sheng Peng and
  • Lee Sprague

Beilstein J. Org. Chem. 2024, 20, 452–459, doi:10.3762/bjoc.20.40

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Published 27 Feb 2024

Synthesis of 2,2-difluoro-1,3-diketone and 2,2-difluoro-1,3-ketoester derivatives using fluorine gas

  • Alexander S. Hampton,
  • David R. W. Hodgson,
  • Graham McDougald,
  • Linhua Wang and
  • Graham Sandford

Beilstein J. Org. Chem. 2024, 20, 460–469, doi:10.3762/bjoc.20.41

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Published 28 Feb 2024

Direct synthesis of acyl fluorides from carboxylic acids using benzothiazolium reagents

  • Lilian M. Maas,
  • Alex Haswell,
  • Rory Hughes and
  • Matthew N. Hopkinson

Beilstein J. Org. Chem. 2024, 20, 921–930, doi:10.3762/bjoc.20.82

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Published 23 Apr 2024
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