Superstructures with cyclodextrins: Chemistry and applications II

  1. editorImage
  1. Editor: Prof. Gerhard Wenz
    Universität des Saarlandes

Cyclodextrins are cyclic oligomeres of anhydroglucose. Since they can be produced through the enzymatic degradation of starch on an industrial scale with high purity, they are now considered to be the most interesting class of organic host molecules. Furthermore, α- and γ-cyclodextrins are known to be nontoxic and are approved as food additives. Since cyclodextrins are soluble in water and able to solubilize hydrophobic active ingredients, they are broadly used in biomedical applications. They are also well known to complex suitable monomeric and polymeric guest molecules, leading to supramolecular structures and topological compounds. The solubility and stability of cyclodextrin complexes are controllable through the derivatization of cyclodextrins. Remarkable progress has been achieved over the past ten years regarding their regioselective derivatization. Many other applications are certain to follow.

See also the Thematic Series:
Superstructures with cyclodextrins: Chemistry and applications IV
Superstructures with cyclodextrins: Chemistry and applications III
Superstructures with cyclodextrins: Chemistry and applications

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Beilstein J. Org. Chem. 2015, 11, 514–523, doi:10.3762/bjoc.11.58

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