Synthesis in the glycosciences

  1. editorImage
  1. Editor: Prof. Thisbe K. Lindhorst
    Christian-Albrechts-Universität zu Kiel

All cells are coated in carbohydrates and glycoconjugates. Today, after decades where sugars were regarded mainly as a means of energy storage or simply as molecular material, it is now known that carbohydrates are deeply involved in cellular communication. This awareness of the biological importance of carbohydrates has led to glycosciences becoming an intriguing and fascinating field of interdisciplinary research. However, the structural diversity found in the carbohydrate regime is unparalleled which makes the biological study of carbohydrate recognition and understanding the processes involved rather complicated. In addition, the multivalent nature of most carbohydrate ligands constitutes a special challenge in glycoscience.

See also the Thematic Series:
Synthesis in the glycosciences II
Multivalent glycosystems for nanoscience

See videos about glycoscience at Beilstein TV.

Synthesis in the glycosciences

  1. Thisbe K. Lindhorst
  • Editorial
  • Published 22 Feb 2010

Beilstein J. Org. Chem. 2010, 6, No. 16, doi:10.3762/bjoc.6.16

Convergent syntheses of LeX analogues

  1. An Wang,
  2. Jenifer Hendel and
  3. France-Isabelle Auzanneau
  • Full Research Paper
  • Published 22 Feb 2010

Beilstein J. Org. Chem. 2010, 6, No. 17, doi:10.3762/bjoc.6.17

  • Full Research Paper
  • Published 22 Feb 2010

  • PDF

Beilstein J. Org. Chem. 2010, 6, No. 18, doi:10.3762/bjoc.6.18

Benzyne arylation of oxathiane glycosyl donors

  1. Martin A. Fascione and
  2. W. Bruce Turnbull
  • Preliminary Communication
  • Published 22 Feb 2010

Beilstein J. Org. Chem. 2010, 6, No. 19, doi:10.3762/bjoc.6.19

(Pseudo)amide-linked oligosaccharide mimetics: molecular recognition and supramolecular properties

  1. José L. Jiménez Blanco,
  2. Fernando Ortega-Caballero,
  3. Carmen Ortiz Mellet and
  4. José M. García Fernández
  • Review
  • Published 22 Feb 2010

  • PDF

Beilstein J. Org. Chem. 2010, 6, No. 20, doi:10.3762/bjoc.6.20

Synthesis of lipophilic 1-deoxygalactonojirimycin derivatives as D-galactosidase inhibitors

  1. Georg Schitter,
  2. Elisabeth Scheucher,
  3. Andreas J. Steiner,
  4. Arnold E. Stütz,
  5. Martin Thonhofer,
  6. Chris A. Tarling,
  7. Stephen G. Withers,
  8. Jacqueline Wicki,
  9. Katrin Fantur,
  10. Eduard Paschke,
  11. Don J. Mahuran,
  12. Brigitte A. Rigat,
  13. Michael Tropak and
  14. Tanja M. Wrodnigg
  • Full Research Paper
  • Published 01 Mar 2010

  • PDF

  • Supp. Info

Beilstein J. Org. Chem. 2010, 6, No. 21, doi:10.3762/bjoc.6.21

  • Full Research Paper
  • Published 04 Mar 2010

  • PDF

  • Supp. Info

Beilstein J. Org. Chem. 2010, 6, No. 23, doi:10.3762/bjoc.6.23

Bioorthogonal metabolic glycoengineering of human larynx carcinoma (HEp-2) cells targeting sialic acid

  1. Arne Homann,
  2. Riaz-ul Qamar,
  3. Sevnur Serim,
  4. Petra Dersch and
  5. Jürgen Seibel
  • Full Research Paper
  • Published 08 Mar 2010

  • PDF

Beilstein J. Org. Chem. 2010, 6, No. 24, doi:10.3762/bjoc.6.24

  • Full Research Paper
  • Published 12 May 2010

  • PDF

  • Supp. Info

Beilstein J. Org. Chem. 2010, 6, No. 47, doi:10.3762/bjoc.6.47

Preparation of aminoethyl glycosides for glycoconjugation

  1. Robert Šardzík,
  2. Gavin T. Noble,
  3. Martin J. Weissenborn,
  4. Andrew Martin,
  5. Simon J. Webb and
  6. Sabine L. Flitsch
  • Full Research Paper
  • Published 29 Jul 2010

Beilstein J. Org. Chem. 2010, 6, 699–703, doi:10.3762/bjoc.6.81

  • Full Research Paper
  • Published 26 Jul 2010

  • PDF

  • Supp. Info

Beilstein J. Org. Chem. 2010, 6, 704–708, doi:10.3762/bjoc.6.80

A bivalent glycopeptide to target two putative carbohydrate binding sites on FimH

  1. Thisbe K. Lindhorst,
  2. Kathrin Bruegge,
  3. Andreas Fuchs and
  4. Oliver Sperling
  • Full Research Paper
  • Published 24 Aug 2010

  • PDF

Beilstein J. Org. Chem. 2010, 6, 801–809, doi:10.3762/bjoc.6.90

En route to photoaffinity labeling of the bacterial lectin FimH

  1. Thisbe K. Lindhorst,
  2. Michaela Märten,
  3. Andreas Fuchs and
  4. Stefan D. Knight
  • Full Research Paper
  • Published 26 Aug 2010

  • PDF

Beilstein J. Org. Chem. 2010, 6, 810–822, doi:10.3762/bjoc.6.91

  • Letter
  • Published 29 Oct 2010

Beilstein J. Org. Chem. 2010, 6, 1022–1024, doi:10.3762/bjoc.6.115

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