A tandem Mannich addition–palladium catalyzed ring-closing route toward 4-substituted-3(2H)-furanones

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• Omanakuttan, V. K.; Valsan, A.; Hopf, H.; John, J. Palladium Catalyzed Ring-Opening of Diazabicylic Olefins with 4-Halo-1,3-Dicarbonyl Compounds: Accessing 3(2H)-Furanone-Appended Cyclopentenes. Organics 2023, 4, 70–85. doi:10.3390/org4010006
• Omanakuttan, V. K.; Santhini, P. V.; Shaludheen, S.; Varughese, S.; Hopf, H.; John, J. Tandem Reaction of 4‐Halo‐1,3‐Dicarbonyl Compounds with Alkynes towards 4‐Vinyl‐3(2H)‐Furanones and 3(2H)‐Furanone fused 2‐Pyridones. Asian Journal of Organic Chemistry 2022, 11. doi:10.1002/ajoc.202200410
• Omanakuttan, V. K.; John, J.; Hopf, H. Synthesis of 3(2H)-Furanones: A Review. European Journal of Organic Chemistry 2020, 2021, 163–201. doi:10.1002/ejoc.202001005
• John, J.; Omanakuttan, V. K.; Aneeja, T.; Suresh, C. H.; Jones, P. G.; Hopf, H. Tandem α-Arylation/Cyclization of 4-Haloacetoacetates with Arynes: A Metal-Free Approach toward 4-Aryl-3-(2H)-furanones. The Journal of organic chemistry 2019, 84, 5957–5964. doi:10.1021/acs.joc.9b00488
• Inagaki, S.; Sato, A.; Sato, H.; Tamura, S.; Kawano, T. Synthesis of 2-substituted 4,5-dihydro-4-oxo-3-furancarboxylates using acylative intramolecular cyclization of sulfonium salts. Tetrahedron Letters 2017, 58, 4872–4875. doi:10.1016/j.tetlet.2017.11.035
• Inagaki, S.; Nakazato, M.; Fukuda, N.; Tamura, S.; Kawano, T. Synthesis of 4-Halo-3(2H)-furanones Using Intramolecular Cyclization of Sulfonium Salts. The Journal of organic chemistry 2017, 82, 5583–5589. doi:10.1021/acs.joc.7b00399
• Zhou, J.; Bai, L.; Liang, G.; Chen, Y.; Gan, Z.; Wang, W.; Zhou, H.; Yu, Y. Organocatalytic asymmetric domino Michael/O-alkylation reaction for the construction of succinimide substituted 3(2H)-furanones catalyzed by quinine. RSC Advances 2017, 7, 39885–39888. doi:10.1039/c7ra07317h

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