Application of Cu(I)-catalyzed azide–alkyne cycloaddition for the design and synthesis of sequence specific probes targeting double-stranded DNA

Svetlana V. Vasilyeva, Vyacheslav V. Filichev and Alexandre S. Boutorine
Beilstein J. Org. Chem. 2016, 12, 1348–1360. https://doi.org/10.3762/bjoc.12.128

Supporting Information

Synthesis and characteristics of the linkers; conditions of azide- and alkyne-modified MGBs synthesis and mass spectral characteristics of the obtained products (1114); synthesis of fluorescent probes based on polyamides and their characteristics (Table S1); synthesis of modified oligonucleotides containing alkyne group (1519) and mass spectrometry identification (Table S2); details of synthesis of Polyamide-TFO conjugates by CuAAC reaction and mass-spectrometry characteristics (Tables S3 and S4, Figure S1) are provided in Supporting Information File 1.

Supporting Information File 1: Experimenal and analytical data.
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Cite the Following Article

Application of Cu(I)-catalyzed azide–alkyne cycloaddition for the design and synthesis of sequence specific probes targeting double-stranded DNA
Svetlana V. Vasilyeva, Vyacheslav V. Filichev and Alexandre S. Boutorine
Beilstein J. Org. Chem. 2016, 12, 1348–1360. https://doi.org/10.3762/bjoc.12.128

How to Cite

Vasilyeva, S. V.; Filichev, V. V.; Boutorine, A. S. Beilstein J. Org. Chem. 2016, 12, 1348–1360. doi:10.3762/bjoc.12.128

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