Supporting Information
| Supporting Information File 1: Experimental part. | ||
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Supporting Information File 2:
IR and NMR spectra.
Supporting Information feature copies of IR and 1H NMR spectra of 7-amino-2,3-dihydro-2-thioxo-1,3-di(2-methoxyphenyl)quinazolin-4(1H)-one (2c) and 1H and 13C NMR spectra of 7-hydroxy-2,3-dihydro-2-thioxo-1,3-di(2-methylphenyl)quinazolin-4(1H)-one (3a). |
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Cite the Following Article
A new and facile synthetic approach to substituted 2-thioxoquinazolin-4-ones by the annulation of a pyrimidine derivative
Nimalini D. Moirangthem and Warjeet S. Laitonjam
Beilstein J. Org. Chem. 2010, 6, 1056–1060.
https://doi.org/10.3762/bjoc.6.120
How to Cite
Moirangthem, N. D.; Laitonjam, W. S. Beilstein J. Org. Chem. 2010, 6, 1056–1060. doi:10.3762/bjoc.6.120
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- S. Laitonjam, W.; Moirangthem, N. Construction of Biologically Active Five- and Six-Membered Fused Ring Pyrimidine Derivatives from 1,3-Diarylthiobarbituric Acids (DTBA). Strategies for the Synthesis of Heterocycles and Their Applications; IntechOpen, 2023. doi:10.5772/intechopen.108842
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- Patil, M. V.; Mhaldar, P. M.; Tayade, S. N.; Rashinkar, G. S.; Pore, D. M. Surfactant based nanoreactor micellar assembly: An innovative route for synthesis of 2-thioxo-2,3-dihydroquinazolin-4(1H)-ones. Journal of Molecular Liquids 2022, 359, 119305. doi:10.1016/j.molliq.2022.119305
- Figueiredo, J.; Serrano, J. L.; Cavalheiro, E.; Keurulainen, L.; Yli-Kauhaluoma, J.; Moreira, V. M.; Ferreira, S.; Domingues, F. C.; Silvestre, S.; Almeida, P. Trisubstituted barbiturates and thiobarbiturates: Synthesis and biological evaluation as xanthine oxidase inhibitors, antioxidants, antibacterial and anti-proliferative agents. European journal of medicinal chemistry 2017, 143, 829–842. doi:10.1016/j.ejmech.2017.11.070
- Šačkus, A.; Kriščiūnienė, V.; Matulevičiūtė, G.; Paliulis, O. Conversion of 2-Thioxo-2,3-dihydroquinazolin-4(1H)-ones to N(3)-Unsubstituted 2-(Het)Arylquinazolin-4(3H)-ones by Copper-Mediated Pd-Catalysed Cross-Coupling Reactions. HETEROCYCLES 2016, 93, 150. doi:10.3987/com-15-s(t)12
- El-Hiti, G. A.; Hussain, A.; Hegazy, A. S.; Alotaibi, M. H. Thioxoquinazoline derivatives: synthesis, reactions and biological activities. Journal of Sulfur Chemistry 2011, 32, 361–395. doi:10.1080/17415993.2011.601417
