4 article(s) from Abe, Ikuro
Graphical Abstract
Figure 1: Examples of endoperoxide-containing natural products.
Scheme 1: Reactions of COXs.
Figure 2: Structures of COXs [52,53]. (A) The overall structure of ovine COX-1. (B and C) Comparison of the cyclooxy...
Scheme 2: Proposed reaction mechanisms of COXs [24].
Scheme 3: General reaction mechanism of Fe/2OG oxygenases.
Scheme 4: Reaction of FtmOx1 [68-71].
Figure 3: Structure of FtmOx1 [71]. (A) The FtmOx1 binary structure in complex with 2OG. (B and C) Comparison of ...
Scheme 5: Proposed COX-like mechanism of FtmOx1 [68].
Scheme 6: Proposed CarC-like mechanism of FtmOx1 [70].
Scheme 7: Reaction of NvfI [28].
Scheme 8: Possible reaction pathways leading to fumigatonoid A [28].
Figure 4: Structure of NvfI [28]. (A–C) Conformational changes of loop regions: (A) open conformation, (B) partia...
Scheme 9: Another possible reaction pathway for the formation of fumigatonoid A [28].
Graphical Abstract
Scheme 1: The regio- and stereoselectivity in quiannulatene and sesterfisherol biosynthesis are determined by...
Scheme 2: Reaction mechanism of quiannulatene biosynthesis. GFPP: geranylfarnesyl diphosphate, IM: intermedia...
Scheme 3: Reaction mechanisms of sesterfisherol biosynthesis. Sesterfisherol is formed by the hydration of IM...
Figure 1: Energy diagram and heat map analysis of 5/12/5 tricycle formation (A) IM1–IM4 in quiannulatene bios...
Figure 2: Energy diagram and heat map analysis of conformational change and hydrogen shift (A) IM4–IM6e in qu...
Figure 3: Energy diagram and heat map analysis of ring rearrangement (A) IM6e–IM11 in quiannulatene biosynthe...
Graphical Abstract
Figure 1: The reactions of aromatic PTases.
Figure 2: The reactions catalyzed by AmbP1 (A) and AmbP3 (B).
Figure 3: The overall structure of apo-AmbP1 (A), the Mg2+-free structure (B), and the Mg2+-bound structure (...
Figure 4: The active site structure of AmbP1. 1 and GSPP were bound in the active site without Mg2+ (A, Mg2+-...
Figure 5: The active site structure of AmbP3 with substrates. The AmbP3 structure in complex with hapalindole...
Figure 6: Multiple amino acid sequence alignment of AmbP1, AmbP3, and other ABBA PTases, visualized by ESPrip...
Graphical Abstract
Figure 1: (A) Schematic representation of pheromone-induced conjugation tube formation for mating in Tremella...
Figure 2: Chemical structures of (A) surfactin A and (B) poly-γ-glutamic acid.
Figure 3: (A) Two types of posttranslational isoprenylations of ComX variants. The modified tryptophan residu...
Figure 4: (A) Schematic representation of the signal transduction cascade of quorum sensing stimulated by the...
Figure 5: Amino acid sequences of ComX from seven Bacillus strains. The sequences of the mature pheromones ar...
Figure 6: Chemical structure of kawaguchipeptin A. Dimethylallylated tryptophan residues are colored blue.