1 article(s) from Boiko, Vladimir N
Examples of industrial fluorine-containing bio-active molecules.
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CF3(S)- and CF3(O)-containing pharmacologically active compounds.
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Hypotensive candidates with SRF and SO2RF groups – analogues of Losartan and Nifedipin.
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The variety of the pharmacological activity of RFS-substituted compounds.
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Recent examples of compounds containing RFS(O)n-groups [12-18].
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Fluorination of ArSCCl3 to corresponding ArSCF3 derivatives. For references see: a[38-43]; b[41,42]; c; d; e[38-43,45-47]; f[38-43,48,49]; g...
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Preparation of aryl pentafluoroethyl sulfides.
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Mild fluorination of the aryl SCF2Br derivatives.
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HF fluorinations of aryl α,α,β-trichloroisobutyl sulfide at various conditions.
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Monofluorination of α,α-dichloromethylene group.
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Electrophilic substitution of phenols with CF3SCl .
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Introduction of SCF3 groups into activated phenols [71-74].
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Preparation of tetrakis(SCF3)-4-methoxyphenol .
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The interactions of resorcinol and phloroglucinol derivatives with RFSCl.
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Reactions of anilines with CF3SCl.
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Trifluoromethylsulfanylation of anilines with electron-donating groups in the meta position .
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Reaction of benzene with CF3SCl/CF3SO3H .
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Reactions of trifluoromethyl sulfenyl chloride with aryl magnesium and -mercury substrates.
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Reactions of pyrroles with CF3SCl.
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Trifluoromethylsulfanylation of indole and indolizines.
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Reactions of N-methylpyrrole with CF3SCl [80,82].
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Reactions of furan, thiophene and selenophene with CF3SCl.
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Trifluoromethylsulfanylation of imidazole and thiazole derivatives .
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Trifluoromethylsulfanylation of pyridine requires initial hydride reduction.
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Introduction of additional RFS-groups into heterocyclic compounds in the presence of CF3SO3H.
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Introduction of additional RFS-groups into pyrroles [82,87].
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By-products in reactions of pyrroles with CF3SCl .
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Reaction of aromatic iodides with CuSCF3 [93,95].
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Reaction of aromatic iodides with RFZCu (Z = S, Se), RF = CF3, C6F5 [93,95,96].
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Side reactions during trifluoromethylsulfanylation of aromatic iodides with CF3SCu .
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Reactions with in situ generated CuSCF3.
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Perfluoroalkylthiolation of aryl iodides with bulky RFSCu .
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In situ formation and reaction of RFZCu with aryl iodides.
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Examples of compounds obtained using in situ generated RFZCu methodology .
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Introduction of SCF3 group into aromatics via difluorocarbene.
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Tetrakis(dimethylamino)ethylene dication trifluoromethyl thiolate as a stable reagent for substitut...
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The use of CF2=S/CsF or (CF3S)2C=S/CsF for the introduction of CF3S groups into fluorinated heteroc...
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One-pot synthesis of ArSCF3 from ArX, CCl2=S and KF.
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Reaction of aromatics with CF3S− Kat+ .
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Reactions of activated aromatic chlorides with AgSCF3/KI.
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Comparative CuSCF3/KI and Hg(SCF3)2/KI reactions.
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Me3SnTeCF3 – a reagent for the introduction of the TeCF3 group.
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Sandmeyer reactions with CuSCF3.
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Reactions of perfluoroalkyl iodides with alkali and organolithium reagents.
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Perfluoroalkylation with preliminary breaking of the disulfide bond.
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Preparation of RFS-substituted anilines from dinitrodiphenyl disulfides.
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Photochemical trifluoromethylation of 2,4,6-trimercaptochlorobenzene .
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Putative process for the formation of B, C and D.
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Trifluoromethylation of 2-mercapto-4-hydroxy-6-trifluoromethylyrimidine .
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Deactivation of 2-mercapto-4-hydroxypyrimidines S-centered radicals.
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Perfluoroalkylation of thiolates with CF3Br under UV irradiation.
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Catalytic effect of methylviologen for RF• generation.
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SO2−• catalyzed trifluoromethylation.
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Electrochemical reduction of CF3Br in the presence of SO2 [199,200].
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Participation of SO2 in the oxidation of ArSCF3−•.
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Electron transfer cascade involving SO2 and MV.
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Four stages of the SRN1 mechanism for thiol perfluoroalkylation.
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A double role of MV in the catalysis of RFI reactions with aryl thiols.
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Photochemical reaction of pentafluoroiodobenzene with trifluoromethyl disulfide.
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N- Trifluoromethyl-N-nitrosobenzene sulfonamide – a source of CF3• radicals [212,213].
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Radical trifluoromethylation of organic disulfides with ArSO2N=NCF3.
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Barton’s S-perfluoroalkylation reactions .
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Decarboxylation of thiohydroxamic esters in the presence of C6F13I.
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Reactions of thioesters of trifluoroacetic and trifluoromethanesulfonic acids in the presence of ar...
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Perfluoroalkylation of polychloropyridine thiols with xenon perfluorocarboxylates or XeF2 [222,223].
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Interaction of Xe(OCORF)2 with nitroaryl disulfide .
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Bi(CF3)3/Cu(OCOCH3)2 trifluoromethylation of thiophenolate .
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Reaction of fluorinated carbanions with aryl sulfenyl chlorides.
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Reaction of methyl perfluoromethacrylate with PhSCl in the presence of fluoride.
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Reactions of ArSCN with potassium and magnesium perfluorocarbanions .
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Reactions of RFI with TDAE and organic disulfides [239,240].
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Decarboxylation of perfluorocarboxylates in the presence of disulfides .
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Organization of a stable form of “CF3−” anion in the DMF.
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Silylated amines in the presence of fluoride can deprotonate fluoroform for reaction with disulfide...
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Other examples of aminomethanols .
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Trifluoromethylation of diphenyl disulfide with PhSO2CF3/t-BuOK.
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Amides of trifluoromethane sulfinic acid are sources of CF3− anion.
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Trifluoromethylation of various thiols using “hyper-valent” iodine (III) reagent .
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Trifluoromethylation of p-nitrothiophenolate with diaryl CF3 sulfonium salts .
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Trifluoromethyl transfer from dibenzo (CF3)S-, (CF3)Se- and (CF3)Te-phenium salts to thiolates .
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Multi-stage paths for synthesis of dibenzo-CF3-thiophenium salts .
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Beilstein J. Org. Chem. 2010, 6, 880–921, doi:10.3762/bjoc.6.88
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