3 article(s) from Crousse, Benoit
A) Natural threonine and its trifluoromethyl analogues sawhorse projections. B) Structure of Boc-pr...
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Synthesis of (2S,3R)-Boc-CF3-Thr(Bzl) 9.
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Synthesis of (2S,3S)-Boc-CF3-Thr 14.
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Synthesis of pentapeptides 1a–4a and 1b–4b.
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Probability distribution of the peptide conformations as a function of end-to-end distance (defined...
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Probability distribution of the peptide dihedral angles ψ for the three central residues Val2 (blac...
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Effects of compounds 1–4 on Aβ1-42 fibrillization assessed by ThT-fluorescence spectroscopy at 10:1...
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Beilstein J. Org. Chem. 2017, 13, 2842–2853, doi:10.3762/bjoc.13.276
Example of bioactive molecules bearing the 2-isoxazoline nucleus.
Synthesis of 3-trifluoromethyl-2-isoxazolines.
Synthesis of aldoxime 2.
Dimerization and isomerization products from nitrile oxides.
Dimerization of 4 yielding bis(trifluoromethyl)furoxan 6.
Depiction of the geometry (left column) and isodensity surface of the reacting frontier molecular o...
FMO energy levels of dipole 4 and dipolarophiles 5a and 5k calculated at the B3LYP/6-31G* level. Co...
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Yields of the cycloaddition reaction plotted against the HOMO energy levels of the dipolarophile pa...
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Beilstein J. Org. Chem. 2013, 9, 2387–2394, doi:10.3762/bjoc.9.275
Synthetic approach to the trifluoromethyl triazoles.
Experimentally found NOE correlation for compound 2c.
Cycloaddition of enantiopure propargylamine.
Beilstein J. Org. Chem. 2008, 4, No. 19, doi:10.3762/bjoc.4.19
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