2 article(s) from Fletcher, Stephen P
Previously reported Cu-AAA of alkylzirconium reagents to racemic allyl chlorides  and this work.
Jump to Scheme 1
DoE from 3,6-dihydro-2H-pyran-3-yl diethyl phosphate (2d). Conditions: 4-phenyl-1-butene (2.5 equiv...
Jump to Figure 1
Scope of nucleophiles. Conditions: alkene (2.5 equiv), Cp2ZrHCl (2.0 equiv), 3-chloro-3,6-dihydro-2H...
Jump to Scheme 2
Reaction kinetics as monitored by in situ 1H NMR spectroscopy from 3-chloro-3,6-dihydro-2H-pyran (2a...
Jump to Figure 2
Reaction kinetics as monitored by in situ 1H NMR spectroscopy from 3,6-dihydro-2H-pyran-3-yl diethy...
Jump to Figure 3
Kinetic ee analysis using 2a. ee of reaction with 3-chloro-3,6-dihydro-2H-pyran (2a) as measured by...
Jump to Figure 4
Kinetic ee analysis using 2d. ee of reaction with 3,6-dihydro-2H-pyran-3-yl diethyl phosphate (2d) ...
Jump to Figure 5
Beilstein J. Org. Chem. 2015, 11, 2435–2443, doi:10.3762/bjoc.11.264
2-Aminoisobutyric acid (Aib).
Alkylation of L-alanine.
Determining enantiomeric purity and absolute configuration of 6*.
Portion of 13C NMR spectrum of 7 showing 2.1:1 ratio of diastereoisomeric isotopomers.
Portion of 13C NMR spectrum of 8 showing location of 13C label in the less shielded methyl group.
Portion of 1H NMR spectrum of 8 showing greater 1JHC coupling in the less shielded methyl group.
Beilstein J. Org. Chem. 2011, 7, 1304–1309, doi:10.3762/bjoc.7.152
Subscribe to our Latest Articles RSS Feed.
Register and get informed about new articles.
Follow the Beilstein-Institut