3 article(s) from Hodgson, David R W
Model reactions of 5′-chloro-5′-deoxyadenosine (1a) with 4-methoxybenzylthiolate salts used to opti...
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Thiolate displacement reactions of 5′-derivatised nucleosides using VBM.
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Selenocyanate displacement reactions of 5′-derivatised nucleosides using liquid-assisted grinding (...
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Beilstein J. Org. Chem. 2017, 13, 87–92, doi:10.3762/bjoc.13.11
Preparation of NDPs.
31P NMR spectrum of TDP 2a after precipitation from reaction mixture.
Attempted use of an isopropylidene-protected 5’-tosylnucleoside.
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Beilstein J. Org. Chem. 2015, 11, 469–472, doi:10.3762/bjoc.11.52
Use of 2-bromoacetic acid esters as heterobifunctional cross-linking agents.
Cross-linking between thiophosphate 4, D-glucosamine (GlcNH2) and bromoacetyl-N-hydroxybenzotriazol...
Ligation of 2-bromoacetic acid esters 1 (R = pNP or mNP) to thiophosphate 4.
Displacement of p- or m-nitrophenolate ions from nitrophenyl esters 7 (R = pNP) and 7 (R = mNP).
log khydrol vs pH for the hydrolysis p-nitrophenyl ester 7 (R = pNP) and m-nitrophenyl ester 7 (R = ...
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log kaminol vs pH for the combined aminolysis and hydrolysis of p-nitrophenyl ester 7 (R = pNP) and ...
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Kinetic model for competing hydrolysis and aminolysis processes of nitrophenyl esters 7 (R = pNP) a...
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Predicted concentration-time profile for the reaction between starting concentrations of 0.05 M p-n...
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Predicted concentration-time profile for the reaction between starting concentrations of 0.05 M m-n...
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Predicted leaving group pKaH values required for user-defined conversion levels of starting concent...
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(A) Direct aminolysis of the ester carbonyl group; (B) intramolecular nucleophilic catalysis of est...
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Beilstein J. Org. Chem. 2010, 6, 732–741, doi:10.3762/bjoc.6.87
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