3 article(s) from Leroux, Frédéric R
Pd-catalyzed monofluoromethylation of pinacol phenylboronate .
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Cu-catalyzed monofluoromethylation with 2-PySO2CHFCOR followed by desulfonylation .
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Cu-catalyzed difluoromethylation with α-silyldifluoroacetates .
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Mechanism of the Cu-catalyzed C–CHF2 bond formation of α,β-unsaturated carboxylic acids through dec...
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Fe-catalyzed decarboxylative difluoromethylation of cinnamic acids .
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Preliminary experiments for investigation of the mechanism of the C–H trifluoromethylation of N-ary...
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Plausible catalytic cycle proposed by Z.-J. Shi et al. for the trifluoromethylation of acetanilides ...
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Plausible catalytic cycle proposed by M. S. Sanford et al. for the perfluoroalkylation of simple ar...
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Postulated reaction pathway for the Ag/Cu-catalyzed trifluoromethylation of aryl iodides by Z. Q. W...
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Postulated reaction mechanism for Cu-catalyzed trifluoromethylation reaction using MTFA as trifluor...
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Formal Heck-type trifluoromethylation of vinyl(het)arenes by M. Sodeoka et al. .
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Proposed catalytic cycle for the copper-catalyzed trifluoromethylation of (het)arenes in presence o...
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Proposed catalytic cycle for the copper-catalyzed trifluoromethylation of N,N-disubstituted (hetero...
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Proposed catalytic cycle by Y. Zhang and J. Wang et al. for the copper-catalyzed trifluoromethylati...
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Mechanistic rationale for the trifluoromethylation of arenes in presence of Langlois’s reagent and ...
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Trifluoromethylation of 4-acetylpyridine with Langlois’s reagent by P. S. Baran et al. (* Stirring ...
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Catalytic copper-facilitated perfluorobutylation of benzene with C4F9I and benzoyl peroxide .
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F.-L. Qing et al.’s proposed mechanism for the copper-catalyzed trifluoromethylation of (hetero)are...
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Mechanism of the Cu-catalyzed/Ru-photocatalyzed trifluoromethylation and perfluoroalkylation of ary...
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Proposed mechanism for the Cu-catalyzed trifluoromethylation of aryl- and vinyl boronic acids with ...
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Possible mechanism for the Cu-catalyzed decarboxylative trifluoromethylation of cinnamic acids .
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Ruthenium-catalyzed perfluoroalkylation of alkenes and (hetero)arenes with perfluoroalkylsulfonyl c...
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N. Kamigata et al.’s proposed mechanism for the Ru-catalyzed perfluoroalkylation of alkenes and (he...
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Proposed mechanism for the Ru-catalyzed photoredox trifluoromethylation of (hetero)arenes with trif...
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Late-stage trifluoromethylation of pharmaceutically relevant molecules with trifluoromethanesulfony...
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Proposed mechanism for the trifluoromethylation of alkenes with trifluoromethyl iodide under Ru-bas...
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Formal perfluoroakylation of terminal alkenes by Ru-catalyzed cross-metathesis with perfluoroalkyle...
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One-pot Ir-catalyzed borylation/Cu-catalyzed trifluoromethylation of complex small molecules by Q. ...
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Mechanistic proposal for the Ni-catalyzed perfluoroalkylation of arenes and heteroarenes with perfl...
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Electrochemical Ni-catalyzed perfluoroalkylation of 2-phenylpyridine (Y. H. Budnikova et al.) .
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Fe(II)-catalyzed trifluoromethylation of arenes and heteroarenes with trifluoromethyl iodide (T. Ya...
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Mechanistic proposal by T. Yamakawa et al. for the Fe(II)-catalyzed trifluoromethylation of arenes ...
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Ytterbium-catalyzed perfluoroalkylation of dihydropyran with perfluoroalkyl iodide (Y. Ding et al.) ...
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Mechanistic proposal by A. Togni et al. for the rhenium-catalyzed trifluoromethylation of arenes an...
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Mechanism of the Cu-catalyzed oxidative trifluoromethylthiolation of arylboronic acids with TMSCF3 ...
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Removal of the 8-aminoquinoline auxiliary .
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Mechanism of the Cu-catalyzed trifluoromethylthiolation of C–H bonds with a trifluoromethanesulfony...
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Beilstein J. Org. Chem. 2013, 9, 2476–2536, doi:10.3762/bjoc.9.287
Modular synthesis of bis(diarylphosphino)-, bis(dialkylphosphino)- and dialkyl(diaryl)phosphinobiph...
Functionalization of 2,2',6-tribromobiphenyl (1a) by regioselective bromine–lithium exchange.
Functionalization of 2,2'-dibromobiphenyls (1b–e) by regioselective bromine–lithium exchange.
General access to biaryl mono- and diphosphine ligands; (Cy = cyclohexyl).
Synthesis of monophosphines 3; (Cy = cyclohexyl).
Molecular structure of compound 3a (crystallized from ethyl acetate/hexane) .
Preparation of mixed dialkyl(diaryl)phosphinobiphenyls 5 via successive bromine–lithium exchange.
Stepwise bromine–lithium exchange on 1c.
Beilstein J. Org. Chem. 2011, 7, 1278–1287, doi:10.3762/bjoc.7.148
Preparation of trifluoromethyl ethers via a chlorination/fluorination sequence.
Preparation of trifluoromethyl ethers via an in situ chlorination/fluorination sequence.
Preparation of trifluoromethyl ethers via chlorothionoformates.
Preparation of trifluoromethyl ethers via fluoroformates.
Oxidative desulfurization-fluorination toward trifluoromethyl ethers.
Mechanism of the oxidative desulfurization-fluorination.
Umemoto's O-(trifluoromethyl)dibenzofuranium salts 4 as CF3-transfer agents.
Togni's approach using hypervalent iodine compounds as CF3-transfer agents.
TAS OCF3 as a nucleophilic OCF3-transfer agent.
Mesomeric structures of the OCF3-group.
Structures of 6 and 7.
Conformational preference of the trifluoromethoxy group on aryl rings.
Nitration of trifluoromethoxy benzene.
Synthesis and Nitration of N-Acetyl-(trifluoromethoxy)anilines.
Bromine/lithium exchange of bromo(trifluoromethoxy)benzenes.
Metalation of (trifluoromethoxy)benzene.
Metalation of (trifluoromethoxy)naphthalenes.
Competition between -CF3- and -OCF3 in Metalation reactions.
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Competition between -F- and -OCF3 in Metalation reactions.
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Metalation of trifluoromethoxyanisoles.
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Direction of π-polarization depending on the substituent as described by Schlosser et al. .
Metalation of Bromo(trifluoromethoxy)benzenes.
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Aryne formation from bromo(trifluoromethoxy)phenyllithiums and subsequent Diels-Alder cycloaddition...
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Metalation of (trifluoromethoxy)anilines.
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Beilstein J. Org. Chem. 2008, 4, No. 13, doi:10.3762/bjoc.4.13
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