6 article(s) from Sandjo, Louis P.
- Full Research Paper
- Published 20 Jul 2017
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Figure 1: Structure of fusaricidins E (1) and F (2).
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Figure 2: NOESY /COSY and HMBC correlations of compound 1.
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Figure 3: Fragmentation pattern of compounds 1 and 2.
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Scheme 1: Retrosynthetic plan for the depsipeptide and GHPD side chain.
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Scheme 2: a) LiAlH4, THF, reflux, 12 h, quant.; b) Fmoc-OSu, NaHCO3, 1,4-dioxane, H2O, 0 °C to rt, 87%; c) 1:...
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Scheme 3: Ester bond formation with 2,2-dimethylated pseudoproline including peptide 16.
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Scheme 4: Cyclization with 2,2-dimethylated pseudoproline including peptide 16.
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Scheme 5: Depsipeptide cyclization and coupling with GHPD side chain.
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Figure 4: Byproducts from removal of Cbz group in THF and DMF.
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- Full Research Paper
- Published 12 Apr 2016
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Figure 1: UPLC profile of the butanol fraction of the leaves of Jungia sellowii after shaking the flask with ...
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Figure 2: Structures of compounds 1–3.
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Figure 3: COSY and HMBC correlations of compounds 1–3.
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Figure 4: NOESY correlations of compounds 1–3.
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Figure 5: ECD spectra of compounds 1–3.
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- Review
- Published 18 Sep 2015
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Figure 1: Fragments produced by the FAB–MS of dehydrokuanoniamine B (20) [42].
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Figure 2: Fragments produced by the EIMS of sagitol (26) [55].
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Figure 3: Fragments produced by the EIMS of styelsamine B (4) [45].
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Figure 4: Fragments produced by the EIMS of styelsamine D (6) [45].
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Figure 5: Fragments produced by the EIMS of subarine (37) [40].
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Scheme 1: Synthesis of styelsamine B (4) and cystodytin J (1) [58].
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Scheme 2: Synthesis of sebastianine A (38) and its regioisomer 39 [59].
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Scheme 3: Synthesis route A of neoamphimedine (12) [61].
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Scheme 4: Synthesis route B of neoamphimedine (12) [62].
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Scheme 5: Synthesis of arnoamines A (40) and B (41) [63].
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Scheme 6: Synthesis of ascididemin (42) [65].
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Scheme 7: Synthesis of subarine (37) [66,67].
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Scheme 8: Synthesis of demethyldeoxyamphimedine (9) [68].
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Scheme 9: Synthesis of pyridoacridine analogues related to ascididemin (42) [70].
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Scheme 10: Synthesis of analogues of meridine (56) [71].
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Scheme 11: Synthesis of bulky pyridoacridine as eilatin (58) [72].
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Scheme 12: Synthesis of AK37 (59), analogue of kuanoniamine A (60) [73].
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Figure 6: Biosynthesis pathway I [74].
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Figure 7: Reaction illustrating catechol and kynuramine as possible biosynthetic precursors [75].
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Figure 8: Biosynthesis pathway B deduced from the feeding experiment A using labelled precursors [76].
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Figure 9: Proposed biosynthesis pathway [47].
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Figure 10: 4H-Pyrido[2,3,4-kl]acridin-4-one as a cytotoxic pharmacophore.
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Figure 11: 7H-Pyrido[2,3,4-kl]acridine as a cytotoxic pharmacophore.
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Figure 12: 9H-Quinolino[4,3,2-de][1,10]phenanthrolin-9-one as a cytotoxic pharmacophore.
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Figure 13: 8H-Benzo[b]pyrido[4,3,2-de][1,7]phenanthrolin-8-one as a cytotoxic pharmacophore.
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Figure 14: Pyrido[4,3,2-mn]pyrrolo[3,2,1-de]acridine as a cytotoxic pharmacophore.
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Figure 15: 9H-Pyrido[4,3,2-mn]thiazolo[4,5-b]acridin-9-one and 8H-pyrido[4,3,2-mn]thiazolo[4,5-b]acridine: cyt...
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Figure 16: 9H-quinolino[4,3,2-de][1,10]phenanthrolin-9-one as an anti-mycobacterial pharmacophore.
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Figure 17: 9H-Quinolino[4,3,2-de][1,10]phenanthrolin-9-one as an antibacterial pharmacophore.
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Figure 18: Saturated and less saturated pyridine moieties as aspartyl inhibitor cores.
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Figure 19: Iminobenzoquinone and acridone cores as intercalating and TOPO inhibitor motifs found in pyridoacri...
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- Full Research Paper
- Published 22 Jan 2014
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Figure 1: HMBC, COSY and NOESY correlations of compound 1.
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Figure 2: HMBC, COSY and NOESY correlations of compound 2.
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Figure 3: HMBC, COSY and NOESY correlations of compound 3.
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Figure 4: HMBC, COSY and NOESY correlations of compound 4.
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Figure 5: Structures of the isolated compounds.
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Figure 6: Crystal structures (ORTEP plot) of arohynapene A (5, left) and tanzawaic acid E (8, right). Thermal...
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- Full Research Paper
- Published 13 Dec 2013
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Figure 1: Structure of SF002-96-1.
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Figure 2: COSY (bold) and HMBC (arrow) correlations of SF002-96-1.
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Figure 3: NOESY correlations of SF002-96-1.
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Figure 4: Effect of SF002-96-1 on survivin promoter activity, survivin mRNA levels and expression. (A) Colo 3...
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Figure 5: Effect of SF002-96-1 on Sat3 and NF-κB binding to the survivin promoter in Colo 320 cells analyzed ...
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Figure 6: SF002-96-1 induces apoptosis of Colo 320 cells. (A) Colo 320 cells were treated without (control) o...
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Figure 7: Single-quadrupole mass spectrumof SF002-96-1 obtained using an atmospheric pressure chemical ioniza...
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- Full Research Paper
- Published 27 Feb 2013
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Figure 1: Known compound sesamin (1) isolated from methylene extract of stem bark of Z. paracanthum.
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Figure 2: COSY, HMBC and NOE correlations of compounds 2, 3 and 4.
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