TY - JOUR A1 - Ingham, Richard J. A1 - Battilocchio, Claudio A1 - Hawkins, Joel M. A1 - Ley, Steven V. T1 - Integration of enabling methods for the automated flow preparation of piperazine-2-carboxamide JF - Beilstein Journal of Organic Chemistry PY - 2014/// VL - 10 SP - 641 EP - 652 SN - 1860-5397 DO - 10.3762/bjoc.10.56 PB - Beilstein-Institut JA - Beilstein J. Org. Chem. UR - https://doi.org/10.3762/bjoc.10.56 KW - automation KW - flow chemistry KW - hydration KW - hydrogenation KW - sustainable processing N2 - Here we describe the use of a new open-source software package and a Raspberry Pi® computer for the simultaneous control of multiple flow chemistry devices and its application to a machine-assisted, multi-step flow preparation of pyrazine-2-carboxamide – a component of Rifater®, used in the treatment of tuberculosis – and its reduced derivative piperazine-2-carboxamide. ER -