TY - JOUR A1 - Huber, Tatjana A1 - Weisheit, Lara A1 - Magauer, Thomas T1 - Synthesis of Xenia diterpenoids and related metabolites isolated from marine organisms JF - Beilstein Journal of Organic Chemistry PY - 2015/// VL - 11 SP - 2521 EP - 2539 SN - 1860-5397 DO - 10.3762/bjoc.11.273 PB - Beilstein-Institut JA - Beilstein J. Org. Chem. UR - https://doi.org/10.3762/bjoc.11.273 KW - asymmetric synthesis KW - natural products KW - total synthesis KW - Xenia diterpenoids KW - xenicanes N2 - This review describes strategies for the chemical synthesis of xenicane diterpenoids and structurally related metabolites. Selected members from the four different subclasses of the Xenia diterpenoid family, the xenicins, xeniolides, xeniaphyllanes and xeniaethers, are presented. The synthetic strategies are discussed with an emphasis on the individual key reactions for the construction of the uncommon nine-membered carbocycle which is the characteristic structural feature of these natural products. Additionally, the putative biosynthetic pathway of xenicanes is illustrated. ER -