TY - JOUR A1 - Jang, Hee Seung A1 - Kim, Yubin A1 - Kim, Dae Young T1 - Enantioselective addition of diphenyl phosphonate to ketimines derived from isatins catalyzed by binaphthyl-modified organocatalysts JF - Beilstein Journal of Organic Chemistry PY - 2016/// VL - 12 SP - 1551 EP - 1556 SN - 1860-5397 DO - 10.3762/bjoc.12.149 PB - Beilstein-Institut JA - Beilstein J. Org. Chem. UR - https://doi.org/10.3762/bjoc.12.149 KW - 3-amino-3-phosphonyl-substituted oxindole KW - α-aminophosphonates KW - bifunctional organocatalyst KW - ketimines KW - organocatalysis KW - squaramide N2 - Chiral binaphthyl-modified squaramide-catalyzed enantioselective addition of diphenyl phosphonate to ketimines derived from isatins has been achieved. This method affords practical and efficient access to chiral 3-amino-3-phosphonyl-substituted oxindole derivatives in high yields with excellent enantioselectivities (up to 99% ee). ER -