TY - JOUR A1 - Aricò, Fabio A1 - Tundo, Pietro T1 - Isosorbide and dimethyl carbonate: a green match JF - Beilstein Journal of Organic Chemistry PY - 2016/// VL - 12 SP - 2256 EP - 2266 SN - 1860-5397 DO - 10.3762/bjoc.12.218 PB - Beilstein-Institut JA - Beilstein J. Org. Chem. UR - https://doi.org/10.3762/bjoc.12.218 KW - carbohydrate chemistry KW - D-sorbitol KW - dimethyl carbonate KW - green chemistry KW - isosorbide N2 - In this review the reactivity of the bio-based platform compounds D-sorbitol and isosorbide with green reagents and solvent dimethyl carbonate (DMC) is reported. Dehydration of D-sorbitol via DMC in the presence of catalytic amounts of base is an efficient and viable process for the preparation of the industrially relevant anhydro sugar isosorbide. This procedure is “chlorine-free”, one-pot, environmental friendly and high yielding. The reactivity of isosorbide with DMC is equally interesting as it can lead to the formation of dicarboxymethyl isosorbide, a potential monomer for isosorbide-based polycarbonate, and dimethyl isosorbide, a high boiling green solvent. The peculiar reactivity of isosorbide and the non-toxic properties of DMC represent indeed a green match leading to several industrial appealing potential applications. ER -