TY - JOUR A1 - Kauscher, Ulrike A1 - Ravoo, Bart Jan T1 - A self-assembled cyclodextrin nanocarrier for photoreactive squaraine JF - Beilstein Journal of Organic Chemistry PY - 2016/// VL - 12 SP - 2535 EP - 2542 SN - 1860-5397 DO - 10.3762/bjoc.12.248 PB - Beilstein-Institut JA - Beilstein J. Org. Chem. UR - https://doi.org/10.3762/bjoc.12.248 KW - cyclodextrin KW - host–guest chemistry KW - photodynamic therapy KW - self-assembly KW - squaraine N2 - Photoreactive squaraines produce cytotoxic oxygen species under irradiation and have significant potential for photodynamic therapy. Herein we report that squaraines can be immobilized on a self-assembled nanocarrier composed of amphiphilic cyclodextrins to enhance their photochemical activity. To this end, a squaraine was equipped with two adamantane moieties that act as anchors for the cyclodextrin vesicle surface. The supramolecular immobilization was monitored by using fluorescence spectroscopy and microscopy and the photochemistry of the squaraine was investigated by using absorption spectroscopy. ER -