TY - JOUR A1 - Xiao, Yan A1 - Jing, Bing A1 - Liu, Xiaoxia A1 - Xue, Hongyu A1 - Liu, Yajun T1 - Metal-free C–H mercaptalization of benzothiazoles and benzoxazoles using 1,3-propanedithiol as thiol source JF - Beilstein Journal of Organic Chemistry PY - 2019/// VL - 15 SP - 279 EP - 284 SN - 1860-5397 DO - 10.3762/bjoc.15.24 PB - Beilstein-Institut JA - Beilstein J. Org. Chem. UR - https://doi.org/10.3762/bjoc.15.24 KW - benzothiazole KW - benzoxazole KW - C–H functionalization KW - mercaptalization KW - 1,3-propanedithiol N2 - A facile and effective C–H functionalization strategy for the synthesis of 2-mercaptobenzothiazoles and 2-mercaptobenzoxazoles is described. 1,3-Propanedithiol was employed to convert benzothiazoles and benzoxazoles to the corresponding heteroarylthiols in the presence of potassium hydroxide and DMSO. This novel protocol is featured by direct C–H mercaptalization of heteroarenes and a simple reaction system. ER -