TY - JOUR A1 - Kobelev, Aleksandr I. A1 - Stepanova, Ekaterina E. A1 - Dmitriev, Maksim V. A1 - Maslivets, Andrey N. T1 - Annulation of 1H-pyrrole-2,3-diones by thioacetamide: an approach to 5-azaisatins JF - Beilstein Journal of Organic Chemistry PY - 2019/// VL - 15 SP - 364 EP - 370 SN - 1860-5397 DO - 10.3762/bjoc.15.32 PB - Beilstein-Institut JA - Beilstein J. Org. Chem. UR - https://doi.org/10.3762/bjoc.15.32 KW - annulation KW - domino reactions KW - isatin KW - nitrogen heterocycles KW - thioamides N2 - A novel approach to 1H-pyrrolo[3,2-c]pyridine-2,3-diones (5-azaisatins) has been developed via an unprecedented annulation of pyrrolo[2,1-c][1,4]benzoxazine-1,2,4-triones by thioacetamide. A new way of C–H functionalization of thioacetamide has been discovered. The reaction proceeds under green catalyst-free conditions. ER -