TY - JOUR A1 - Kamlar, Martin A1 - Reiberger, Robert A1 - Nigríni, Martin A1 - Císařová, Ivana A1 - Veselý, Jan T1 - Enantioselective PCCP Brønsted acid-catalyzed aminalization of aldehydes JF - Beilstein Journal of Organic Chemistry PY - 2021/// VL - 17 SP - 2433 EP - 2440 SN - 1860-5397 DO - 10.3762/bjoc.17.160 PB - Beilstein-Institut JA - Beilstein J. Org. Chem. UR - https://doi.org/10.3762/bjoc.17.160 KW - aminalization KW - Brønsted acid KW - organocatalysis KW - PCCP KW - pentacarboxycyclopentadiene N2 - Here we present an enantioselective aminalization of aldehydes catalyzed by Brønsted acids based on pentacarboxycyclopentadienes (PCCPs). The cyclization reaction using readily available anthranilamides as building blocks provides access to valuable 2,3-dihydroquinazolinones containing one stereogenic carbon center with good enantioselectivity (ee up to 80%) and excellent yields (up to 97%). ER -