TY - JOUR A1 - Kawanishi, Ryouta A1 - Nakada, Kosuke A1 - Shibatomi, Kazutaka T1 - Decarboxylative trifluoromethylthiolation of pyridylacetates JF - Beilstein Journal of Organic Chemistry PY - 2021/// VL - 17 SP - 229 EP - 233 SN - 1860-5397 DO - 10.3762/bjoc.17.23 PB - Beilstein-Institut JA - Beilstein J. Org. Chem. UR - https://doi.org/10.3762/bjoc.17.23 KW - decarboxylation KW - fluorinated compounds KW - pyridine compounds KW - trifluoromethylthiolation N2 - Decarboxylative trifluoromethylthiolation of lithium pyridylacetates was achieved using N-(trifluoromethylthio)benzenesulfonimide as the electrophilic trifluoromethylthiolation reagent. The reaction afforded the corresponding trifluoromethyl thioethers in good yield. Furthermore, the preparation of lithium pyridylacetates by saponification of the corresponding methyl esters and subsequent decarboxylative trifluoromethylthiolation were performed in a one-pot fashion. ER -