TY - JOUR A1 - Shabalin, Dmitrii A. A1 - Ivanova, Evgeniya E. A1 - Ushakov, Igor A. A1 - Schmidt, Elena Yu. A1 - Trofimov, Boris A. T1 - Hydrazides in the reaction with hydroxypyrrolines: less nucleophilicity – more diversity JF - Beilstein Journal of Organic Chemistry PY - 2021/// VL - 17 SP - 319 EP - 324 SN - 1860-5397 DO - 10.3762/bjoc.17.29 PB - Beilstein-Institut JA - Beilstein J. Org. Chem. UR - https://doi.org/10.3762/bjoc.17.29 KW - hydrazides KW - pyridazines KW - pyrrolines KW - recyclization KW - ring expansion N2 - Expedient protocols for the synthesis of three types of highly functionalized azaheterocyclic scaffolds (dihydropyridazines, tetrahydropyridazines, and partially saturated tricyclic systems) from readily available hydroxypyrrolines and hydrazides are described. The directions of the transformation of a common initial intermediate, namely a Brønsted acid-activated hydroxypyrroline, depend on the reaction conditions and the structure of the hydrazides. ER -