TY - JOUR A1 - Tong, Qingzhe A1 - Zhao, Zhiguo A1 - Wang, Yao T1 - A Se···O bonding catalysis approach to the synthesis of calix[4]pyrroles JF - Beilstein Journal of Organic Chemistry PY - 2022/// VL - 18 SP - 325 EP - 330 SN - 1860-5397 DO - 10.3762/bjoc.18.36 PB - Beilstein-Institut JA - Beilstein J. Org. Chem. UR - https://doi.org/10.3762/bjoc.18.36 KW - calix[4]pyrrole KW - chalcogen bonding KW - ketones KW - Se···O bonding interactions KW - supramolecular catalysis N2 - Described herein is a chalcogen bonding catalysis approach to the synthesis of calix[4]pyrrole derivatives. The Se···O bonding interactions between selenide catalysts and ketones gave rise to the catalytic activity in the condensation reactions between pyrrole and ketones, leading to the generation of calix[4]pyrrole derivatives in moderate to high yields. This chalcogen bonding catalysis approach was efficient since only 5 mol % catalyst loading was used to promote the consecutive condensation processes while the reactions could be carried out at room temperature, thus highlighting the potential of this type of nonclassical interactions in catalyzing relative complex transformations. ER -