TY - JOUR A1 - Esposito, Davide A1 - Hurevich, Mattan A1 - Castagner, Bastien A1 - Wang, Cheng-Chung A1 - Seeberger, Peter H. T1 - Automated synthesis of sialylated oligosaccharides JF - Beilstein Journal of Organic Chemistry PY - 2012/// VL - 8 SP - 1601 EP - 1609 SN - 1860-5397 DO - 10.3762/bjoc.8.183 PB - Beilstein-Institut JA - Beilstein J. Org. Chem. UR - https://doi.org/10.3762/bjoc.8.183 KW - automated synthesis KW - disaccharide building blocks KW - solid-phase synthesis KW - sialic acid KW - sialosides N2 - Sialic acid-containing glycans play a major role in cell-surface interactions with external partners such as cells and viruses. Straightforward access to sialosides is required in order to study their biological functions on a molecular level. Here, automated oligosaccharide synthesis was used to facilitate the preparation of this class of biomolecules. Our strategy relies on novel sialyl α-(2→3) and α-(2→6) galactosyl imidates, which, used in combination with the automated platform, provided rapid access to a small library of conjugation-ready sialosides of biological relevance. ER -