TY - JOUR A1 - Grundmann, Florian A1 - Dill, Veronika A1 - Dowling, Andrea A1 - Thanwisai, Aunchalee A1 - Bode, Edna A1 - Chantratita, Narisara A1 - ffrench-Constant, Richard A1 - Bode, Helge B. T1 - Identification and isolation of insecticidal oxazoles from Pseudomonas spp. JF - Beilstein Journal of Organic Chemistry PY - 2012/// VL - 8 SP - 749 EP - 752 SN - 1860-5397 DO - 10.3762/bjoc.8.85 PB - Beilstein-Institut JA - Beilstein J. Org. Chem. UR - https://doi.org/10.3762/bjoc.8.85 KW - insecticidal activity KW - labradorin KW - oxazole KW - Pseudomonas KW - secondary metabolite N2 - Two new and five known oxazoles were identified from two different Pseudomonas strains in addition to the known pyrones pseudopyronine A and B. Labeling experiments confirmed their structures and gave initial evidence for a novel biosynthesis pathway of these natural oxazoles. In order to confirm their structure, they were synthesized, which also allowed tests of their bioactivity. Additionally, the bioactivities of the synthesis intermediates were also investigated revealing interesting biological activities for several compounds despite their overall simple structures. ER -