TY - JOUR A1 - Kawano, Shintaro A1 - Kida, Toshiyuki A1 - Akashi, Mitsuru A1 - Sato, Hirofumi A1 - Shizuma, Motohiro A1 - Ono, Daisuke T1 - Preparation of Pickering emulsions through interfacial adsorption by soft cyclodextrin nanogels JF - Beilstein Journal of Organic Chemistry PY - 2015/// VL - 11 SP - 2355 EP - 2364 SN - 1860-5397 DO - 10.3762/bjoc.11.257 PB - Beilstein-Institut JA - Beilstein J. Org. Chem. UR - https://doi.org/10.3762/bjoc.11.257 KW - crosslinked cyclodextrin polymer KW - interfacial adsorption KW - nanogel KW - Pickering emulsion N2 - Background: Emulsions stabilized by colloidal particles are known as Pickering emulsions. To date, soft microgel particles as well as inorganic and organic particles have been utilized as Pickering emulsifiers. Although cyclodextrin (CD) works as an attractive emulsion stabilizer through the formation of a CD–oil complex at the oil–water interface, a high concentration of CD is normally required. Our research focuses on an effective Pickering emulsifier based on a soft colloidal CD polymer (CD nanogel) with a unique surface-active property.Results: CD nanogels were prepared by crosslinking heptakis(2,6-di-O-methyl)-β-cyclodextrin with phenyl diisocyanate and subsequent immersion of the resulting polymer in water. A dynamic light scattering study shows that primary CD nanogels with 30–50 nm diameter assemble into larger CD nanogels with 120 nm diameter by an increase in the concentration of CD nanogel from 0.01 to 0.1 wt %. The CD nanogel has a surface-active property at the air–water interface, which reduces the surface tension of water. The CD nanogel works as an effective Pickering emulsion stabilizer even at a low concentration (0.1 wt %), forming stable oil-in-water emulsions through interfacial adsorption by the CD nanogels.Conclusion: Soft CD nanogel particles adsorb at the oil–water interface with an effective coverage by forming a strong interconnected network and form a stable Pickering emulsion. The adsorption property of CD nanogels on the droplet surface has great potential to become new microcapsule building blocks with porous surfaces. These microcapsules may act as stimuli-responsive nanocarriers and nanocontainers. ER - TY - JOUR AU - Pickering, S. U. JF - J. Chem. Soc., Trans. PY - 1907/// VL - 91 SP - 2001 EP - 2021 DO - 10.1039/ct9079102001 ER - TY - JOUR AU - Finkle, P. AU - Draper, H. D. AU - Hildebrand, J. H. JF - J. Am. Chem. Soc. PY - 1923/// VL - 45 SP - 2780 EP - 2788 DO - 10.1021/ja01665a002 ER - TY - JOUR AU - Binks, B. P. AU - Lumsdon, S. O. 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