Beilstein Talk on ROS generation by photoexcited fullerenes

Beilstein Talks

The Beilstein Talks are a popular addition to the project portfolio of the Beilstein-Institut. The goal of this webinar series is to support communication, discussion, and the exchange of information in the chemical sciences. While Beilstein Talks are always free to attend, registration is straightforward and required to attend these live events.

ROS generation by photoexcited fullerenes

Online live talk by

Yoko Yamakoshi
/ ETH Zurich, Switzerland
June 15
, 2023, 3–4 pm CEST

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Since the discovery of C60 in 1985, photoinduced reactions by fullerenes have been studied since the early 1990’s.  Important properties of fullerenes as photosensitizers (PSs) include excitation wavelength in the relatively long wavelength region and efficient generation of ROSs. Coupled with the lack of reported toxicity of C60 in the dark in mammalians, these properties render fullerenes suitable for photodynamic therapy (PDT)-PS. To use C60 in biological systems, several approached have been developed to prepare water-soluble complex or derivatives. In this study, 1,3-dipolar cycloaddition reactions of C60, C70 and M3N@C80 for the preparation of water-soluble fullerene derivatives and their use for ROS generation, as well as applications of these systems will be discussed.

09 May 2023

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