Asymmetric reactions in continuous flow

Scholarly Works

• Sugita, S.; Ishitani, H.; Kobayashi, S. A Practical and Convenient Synthesis of the Essential Antibiotic Drug Cefazolin under Sequential One-Flow Conditions. Bulletin of the Chemical Society of Japan 2023, 96, 744–751. doi:10.1246/bcsj.20230113
• Ishitani, H.; Saito, Y.; Kobayashi, S. doi:10.1002/9781119736424.ch22
• Wang, L.; Huang, Z.; Yang, X.; Rogée, L.; Huang, X.; Zhang, X.; Lau, S. P. Review on optofluidic microreactors for photocatalysis. Reviews in Chemical Engineering 2022, 39, 765–782. doi:10.1515/revce-2021-0068
• Burange, A. S.; Osman, S. M.; Luque, R. Understanding flow chemistry for the production of active pharmaceutical ingredients. iScience 2022, 25, 103892. doi:10.1016/j.isci.2022.103892
• Saito, Y.; Nishizawa, K.; Laroche, B.; Ishitani, H.; Kobayashi, S. Continuous-Flow Synthesis of (R)-Tamsulosin Utilizing Sequential Heterogeneous Catalysis. Angewandte Chemie (International ed. in English) 2022, 61, e202115643. doi:10.1002/anie.202115643
• Saito, Y.; Nishizawa, K.; Laroche, B.; Ishitani, H.; Kobayashi, S. Continuous‐Flow Synthesis of (R)‐Tamsulosin Utilizing Sequential Heterogeneous Catalysis. Angewandte Chemie 2022, 134. doi:10.1002/ange.202115643
• Saito, Y.; Kobayashi, S. Chiral Heterogeneous Scandium Lewis Acid Catalysts for Continuous-Flow Enantioselective Friedel–Crafts Carbon–Carbon Bond-Forming Reactions. Angewandte Chemie (International ed. in English) 2021, 60, 26566–26570. doi:10.1002/anie.202112797
• Saito, Y.; Kobayashi, S. Chiral Heterogeneous Scandium Lewis Acid Catalysts for Continuous‐Flow Enantioselective Friedel–Crafts Carbon–Carbon Bond‐Forming Reactions. Angewandte Chemie 2021, 133, 26770–26774. doi:10.1002/ange.202112797
• Farkas, G.; Madarász, J.; Bakos, J. Asymmetric Hydrogenation and Transfer Hydrogenation; Wiley, 2021; pp 307–337. doi:10.1002/9783527822294.ch10
• De Santis, P.; Meyer, L.-E.; Kara, S. The rise of continuous flow biocatalysis – fundamentals, very recent developments and future perspectives. Reaction Chemistry & Engineering 2020, 5, 2155–2184. doi:10.1039/d0re00335b
• Xiaofei, T.; Zhao, J.; Wu, Y.; Zheng, Z.-H.; Ma, C.; Yu, Z.; Yun, L.; Guangzhi, L.; Meng, Q. Asymmetric α-hydroxylation of β-dicarbonyl compounds by C-2′ modified cinchonine-derived phase-transfer catalysts in batch and flow microreactors. Synthetic Communications 2020, 50, 2478–2487. doi:10.1080/00397911.2020.1781183
• De Risi, C.; Bortolini, O.; Brandolese, A.; Di Carmine, G.; Ragno, D.; Massi, A. Recent advances in continuous-flow organocatalysis for process intensification. Reaction Chemistry & Engineering 2020, 5, 1017–1052. doi:10.1039/d0re00076k
• Brill, Z. G.; Ritts, C. B.; Mansoor, U. F.; Sciammetta, N. Continuous Flow Enables Metallaphotoredox Catalysis in a Medicinal Chemistry Setting: Accelerated Optimization and Library Execution of a Reductive Coupling between Benzylic Chlorides and Aryl Bromides. Organic letters 2019, 22, 410–416. doi:10.1021/acs.orglett.9b04117
• Myachin, I. V.; Orlova, A. V.; Kononov, L. O. Glycosylation in flow: effect of the flow rate and type of the mixer. Russian Chemical Bulletin 2019, 68, 2126–2129. doi:10.1007/s11172-019-2677-y
• van den Biggelaar, L.; Soumillion, P.; Debecker, D. P. Biocatalytic transamination in a monolithic flow reactor: improving enzyme grafting for enhanced performance. RSC advances 2019, 9, 18538–18546. doi:10.1039/c9ra02433f
• de la Torre, A. F.; Scatena, G. S.; Valdés, O.; Rivera, D. G.; Paixão, M. W. Ugi reaction-derived prolyl peptide catalysts grafted on the renewable polymer polyfurfuryl alcohol for applications in heterogeneous enamine catalysis. Beilstein journal of organic chemistry 2019, 15, 1210–1216. doi:10.3762/bjoc.15.118
• Zhang, J.; Chen, J.; Peng, S.; Peng, S.; Zhang, Z.; Tong, Y.; Miller, P. W.; Yan, X.-P. Emerging porous materials in confined spaces: from chromatographic applications to flow chemistry. Chemical Society reviews 2019, 48, 2566–2595. doi:10.1039/c8cs00657a
• Landeros, J. M.; Suchy, L.; Avila-Ortiz, C. G.; Maulide, N.; Juaristi, E. Dendrimeric α,β-dipeptidic conjugates as organocatalysts in the asymmetric Michael addition reaction of isobutyraldehyde to N-phenylmaleimides. Monatshefte für Chemie - Chemical Monthly 2019, 150, 777–788. doi:10.1007/s00706-018-2338-0
• Szabó, B.; Tamás, B.; Faigl, F.; Éles, J.; Greiner, I. Diastereoselective synthesis of cis-N-Boc-4-aminocyclohexanol with reductive ring opening method using continuous flow. Journal of Flow Chemistry 2019, 9, 13–17. doi:10.1007/s41981-018-00028-3
• Laroche, B.; Ishitani, H.; Kobayashi, S. Direct Reductive Amination of Carbonyl Compounds with H2 Using Heterogeneous Catalysts in Continuous Flow as an Alternative to N-Alkylation with Alkyl Halides. Advanced Synthesis & Catalysis 2018, 360, 4699–4704. doi:10.1002/adsc.201801457

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