These Thematic Series are open for submission: (1) Chemical Biology; (2) Organic Porous Materials

Submission is open for “Spatial Effects in Polymer Chemistry”, edited by Helmut Ritter.

The 2015 Impact Factor is 2.697 according to the Thomson Reuters Journal Citation Reports.

Open Access 2020 is an initiative to induce the transformation from subscription to open access publishing.

Confirming exceptionally high level of publishing standards


Automated chemical synthesis


Editor: Prof. Ian R. Baxendale
Durham University

This Thematic Series presents the latest research results in automated chemical synthesis.

Further articles will be published during the next weeks.




 
Overview

Automated glycan assembly of a S. pneumoniae serotype 3 CPS antigen

Markus W. Weishaupt, Stefan Matthies, Mattan Hurevich, Claney L. Pereira, Heung Sik Hahm, Peter H. Seeberger

Beilstein J. Org. Chem. 2016, 12, 1440–1446. published 12 Jul 2016

Full Research Paper

Flow carbonylation of sterically hindered ortho-substituted iodoarenes

Carl J. Mallia, Gary C. Walter, Ian R. Baxendale

Beilstein J. Org. Chem. 2016, 12, 1503–1511. published 19 Jul 2016

Full Research Paper

Catalytic Chan–Lam coupling using a ‘tube-in-tube’ reactor to deliver molecular oxygen as an oxidant

Carl J. Mallia, Paul M. Burton, Alexander M. R. Smith, Gary C. Walter, Ian R. Baxendale

Beilstein J. Org. Chem. 2016, 12, 1598–1607. published 26 Jul 2016

Full Research Paper

The in situ generation and reactive quench of diazonium compounds in the synthesis of azo compounds in microreactors

Faith M. Akwi, Paul Watts

Beilstein J. Org. Chem. 2016, 12, 1987–2004. published 06 Sep 2016

Full Research Paper

Development of a continuous process for α-thio-β-chloroacrylamide synthesis with enhanced control of a cascade transformation

Olga C. Dennehy, Valérie M. Y. Cacheux, Benjamin J. Deadman, Denis Lynch, Stuart G. Collins, Humphrey A. Moynihan, Anita R. Maguire

Beilstein J. Org. Chem. 2016, 12, 2511–2522. published 24 Nov 2016

Full Research Paper

The digital code driven autonomous synthesis of ibuprofen automated in a 3D-printer-based robot

Philip J. Kitson, Stefan Glatzel, Leroy Cronin

Beilstein J. Org. Chem. 2016, 12, 2776–2783. published 19 Dec 2016

Full Research Paper

Extrusion – back to the future: Using an established technique to reform automated chemical synthesis

Deborah E. Crawford

Beilstein J. Org. Chem. 2017, 13, 65–75. published 11 Jan 2017

Review

Solution-phase automated synthesis of an α-amino aldehyde as a versatile intermediate

Hisashi Masui, Sae Yosugi, Shinichiro Fuse, Takashi Takahashi

Beilstein J. Org. Chem. 2017, 13, 106–110. published 17 Jan 2017

Letter

3D printed fluidics with embedded analytic functionality for automated reaction optimisation

Andrew J. Capel, Andrew Wright, Matthew J. Harding, George W. Weaver, Yuqi Li, Russell A. Harris, Steve Edmondson, Ruth D. Goodridge, Steven D. R. Christie

Beilstein J. Org. Chem. 2017, 13, 111–119. published 18 Jan 2017

Full Research Paper

Diels–Alder reactions of myrcene using intensified continuous-flow reactors

Christian H. Hornung, Miguel Á. Álvarez-Diéguez, Thomas M. Kohl, John Tsanaktsidis

Beilstein J. Org. Chem. 2017, 13, 120–126. published 19 Jan 2017

Full Research Paper

Self-optimisation and model-based design of experiments for developing a C–H activation flow process

Alexander Echtermeyer, Yehia Amar, Jacek Zakrzewski, Alexei Lapkin

Beilstein J. Org. Chem. 2017, 13, 150–163. published 24 Jan 2017

Full Research Paper

Continuous-flow synthesis of highly functionalized imidazo-oxadiazoles facilitated by microfluidic extraction

Ananda Herath, Nicholas D. P. Cosford

Beilstein J. Org. Chem. 2017, 13, 239–246. published 07 Feb 2017

Full Research Paper

NMR reaction monitoring in flow synthesis

M. Victoria Gomez, Antonio de la Hoz

Beilstein J. Org. Chem. 2017, 13, 285–300. published 14 Feb 2017

Review

A chemoselective and continuous synthesis of m-sulfamoylbenzamide analogues

Arno Verlee, Thomas Heugebaert, Tom van der Meer, Pavel I. Kerchev, Frank Van Breusegem, Christian V. Stevens

Beilstein J. Org. Chem. 2017, 13, 303–312. published 16 Feb 2017

Full Research Paper

Continuous N-alkylation reactions of amino alcohols using γ-Al2O3 and supercritical CO2: unexpected formation of cyclic ureas and urethanes by reaction with CO2

Emilia S. Streng, Darren S. Lee, Michael W. George, Martyn Poliakoff

Beilstein J. Org. Chem. 2017, 13, 329–337. published 21 Feb 2017

Full Research Paper