Transition-metal-catalyzed domino reactions of strained bicyclic alkenes

• Austin Pounder,
• Eric Neufeld,
• Peter Myler and
• William Tam

Beilstein J. Org. Chem. 2023, 19, 487–540, doi:10.3762/bjoc.19.38

Iron-catalyzed domino coupling reactions of π-systems

• Austin Pounder and
• William Tam

Beilstein J. Org. Chem. 2021, 17, 2848–2893, doi:10.3762/bjoc.17.196

An overview on disulfide-catalyzed and -cocatalyzed photoreactions

• Yeersen Patehebieke

Beilstein J. Org. Chem. 2020, 16, 1418–1435, doi:10.3762/bjoc.16.118

• , mild, and chemoselective radical catalysts that deserve more attention. The present review highlights the recent progress in the field of disulfide-catalyzed and -cocatalyzed photocatalytic reactions for different reaction types. Keywords: cycloaddition; disulfide catalyst; isomerization; oxidation

• synthesize alcohols, and realizing the anti-Markovnikov regioselectivity is extremely challenging. In 2017, Lei and co-workers reported a class of disulfide-cocatalyzed anti-Markovnikov olefin hydration reactions [24]. In this reaction, 9-mesityl-10-methylacridinium (Acr+–Mes–ClO4−) and diphenyl disulfide

• disulfide. Disulfide-cocatalyzed anti-Markovnikov olefin hydration reactions. Disulfide-catalyzed decarboxylation of carboxylic acids. Proposed mechanism of the disulfide-catalyzed decarboxylation of carboxylic acids. Disulfide-catalyzed decarboxylation of carboxylic acids. Disulfide-catalyzed conversion of

Copper-catalyzed enantioselective conjugate addition of organometallic reagents to challenging Michael acceptors

• Delphine Pichon,
• Jennifer Morvan,
• Christophe Crévisy and
• Marc Mauduit

Beilstein J. Org. Chem. 2020, 16, 212–232, doi:10.3762/bjoc.16.24

• enantioselective synthesis of valnoctamide, a commercialized mild tranquilizer. Finally, this methodology was extended to the sequential Michael/halogenation reaction using NFSI or NCS as electrophiles, with similar efficiency. Similarly, a cocatalyzed enantioselective β-functionalization of enals was developed by

Electron-deficient pyridinium salts/thiourea cooperative catalyzed O-glycosylation via activation of O-glycosyl trichloroacetimidate donors

• Mukta Shaw,
• Yogesh Kumar,
• Rima Thakur and
• Amit Kumar

Beilstein J. Org. Chem. 2017, 13, 2385–2395, doi:10.3762/bjoc.13.236

• -deficient pyridinium salt/thiourea cocatalyzed glycosidation is outlined in Figure 4. It is presumed that at first electron-deficient pyridinium salt 3a undergoes 1,2-addition with the acceptor to produce ammonium salt X. The addition of the thiourea derivative as hydrogen-bonding cocatalyst could activate

Preparation of phosphines through C–P bond formation

• Iris Wauters,
• Wouter Debrouwer and
• Christian V. Stevens

Beilstein J. Org. Chem. 2014, 10, 1064–1096, doi:10.3762/bjoc.10.106

Recent advances in transition-metal-catalyzed intermolecular carbomagnesiation and carbozincation

• Kei Murakami and
• Hideki Yorimitsu

Beilstein J. Org. Chem. 2013, 9, 278–302, doi:10.3762/bjoc.9.34

• Hayashi reported iron/copper cocatalyzed alkene–Grignard exchange reactions and their application to one-pot alkylmagnesiation of alkynes (Scheme 30) [104]. The exchange reactions proceeded through a β-hydrogen elimination–hydromagnesiation sequence to generate 4c. The alkylmagnesiation reactions of 1

• zirconium salt, the examples of transition-metal-catalyzed carbometalation of dialkylacetylenes were limited only to carboboration [109][110] and carbostannylation [111]. In 2005, Shirakawa and Hayashi reported iron/copper-cocatalyzed arylmagnesiation of dialkylacetylenes [112]. This is the first successful

• -catalyzed carbozincation of arylacetylenes and its application to the synthesis of tamoxifen. Bristol-Myers Squibb’s nickel-catalyzed phenylzincation. Iron/NHC-catalyzed arylmagnesiation of aryl(alkyl)acetylene. Iron/copper-cocatalyzed alkylmagnesiation of aryl(alkyl)acetylenes. Iron-catalyzed

Asymmetric one-pot sequential Friedel–Crafts-type alkylation and α-oxyamination catalyzed by a peptide and an enzyme

• Kengo Akagawa,
• Ryota Umezawa and
• Kazuaki Kudo

Beilstein J. Org. Chem. 2012, 8, 1333–1337, doi:10.3762/bjoc.8.152

• -oxyamination of aldehydes catalyzed by a peptide and an oxidizing enzyme, laccase [36][38]. Because the reaction conditions for that system are mild without employing a strong oxidant, we envisaged that the sequential FCAA/α-oxygenation could be attained by adopting the peptide-and-laccase-cocatalyzed

Efficient gold(I)/silver(I)-cocatalyzed cascade intermolecular N-Michael addition/intramolecular hydroalkylation of unactivated alkenes with α-ketones

• Ya-Ping Xiao,
• Xin-Yuan Liu and
• Chi-Ming Che

Beilstein J. Org. Chem. 2011, 7, 1100–1107, doi:10.3762/bjoc.7.126

• Open Laboratory of Chemical Biology of the Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong, P. R. China 10.3762/bjoc.7.126 Abstract The gold(I)/silver(I)-cocatalyzed cascade intermolecular N-Michael addition/intramolecular

• AgClO4 catalyzed intermolecular N-Michael addition and the subsequent gold(I)-catalyzed hydroalkylation is proposed. Keywords: cascade; cocatalyzed; gold(I)-catalyzed; intramolecular hydroalkylation; intermolecular N-Michael addition; pyrrolidine; silver(I)-catalyzed; Introduction Gold complexes are

• -cocatalysis see [39] and for Au/Rh-cocatalysis see [40]). However, the use of homogeneous gold catalysts in cooperation with other metal catalysts has been reported only in a few cases [30][31][32][33][34][35][36][37][38][39][40]. In this work, we describe a highly efficient gold(I)/silver(I)-cocatalyzed