C–H Functionalization

  1. editorImage
  1. Editor: Prof. Huw M. L. Davies
    Emory University

C–H Functionalization has the potential to become a paradigmshifting strategy for organic synthesis. Over the last decade, the field has experienced explosive growth and a large variety of new C–H functionalization methodologies have been developed. In particular, regioselective functionalization of sp2 C–H bonds has become a broadly flexible approach for the synthesis of complex aromatic carbocycles and heterocycles. The selective functionalization of sp3C–H bonds is a more challenging proposition, but in recent years significant advances have been made to suggest that even these types of transformations can become broadly applicable. This Thematic Series highlights some of the novel approaches that are applied to the field of C–H functionalization and it covers topics that range from novel catalyst design, new synthetic methods, and cascade sequences that incorporate C–H functionalization.

See also the Thematic Series:
C–H Functionalization/activation in organic synthesis

C–H Functionalization

  1. Huw M. L. Davies
  • Editorial
  • Published 18 Sep 2012

Beilstein J. Org. Chem. 2012, 8, 1552–1553, doi:10.3762/bjoc.8.176

  • Letter
  • Published 14 Sep 2012

Beilstein J. Org. Chem. 2012, 8, 1536–1542, doi:10.3762/bjoc.8.174

  • Review
  • Published 18 Sep 2012

  • PDF

  • Supp. Info

Beilstein J. Org. Chem. 2012, 8, 1554–1563, doi:10.3762/bjoc.8.177

  • Letter
  • Published 18 Sep 2012

Beilstein J. Org. Chem. 2012, 8, 1564–1568, doi:10.3762/bjoc.8.178

  • Full Research Paper
  • Published 18 Sep 2012

  • PDF

  • Supp. Info

Beilstein J. Org. Chem. 2012, 8, 1569–1575, doi:10.3762/bjoc.8.179

Extending the utility of [Pd(NHC)(cinnamyl)Cl] precatalysts: Direct arylation of heterocycles

  1. Anthony R. Martin,
  2. Anthony Chartoire,
  3. Alexandra M. Z. Slawin and
  4. Steven P. Nolan
  • Full Research Paper
  • Published 27 Sep 2012

  • PDF

  • Supp. Info

Beilstein J. Org. Chem. 2012, 8, 1637–1643, doi:10.3762/bjoc.8.187

  • Review
  • Published 11 Oct 2012

  • PDF

Beilstein J. Org. Chem. 2012, 8, 1730–1746, doi:10.3762/bjoc.8.198

  • Full Research Paper
  • Published 16 Oct 2012

  • PDF

  • Supp. Info

Beilstein J. Org. Chem. 2012, 8, 1771–1777, doi:10.3762/bjoc.8.202

Rh(III)-catalyzed directed C–H bond amidation of ferrocenes with isocyanates

  1. Satoshi Takebayashi,
  2. Tsubasa Shizuno,
  3. Takashi Otani and
  4. Takanori Shibata
  • Letter
  • Published 29 Oct 2012

Beilstein J. Org. Chem. 2012, 8, 1844–1848, doi:10.3762/bjoc.8.212

Alkyne hydroarylation with Au N-heterocyclic carbene catalysts

  1. Cristina Tubaro,
  2. Marco Baron,
  3. Andrea Biffis and
  4. Marino Basato
  • Full Research Paper
  • Published 05 Feb 2013

  • PDF

Beilstein J. Org. Chem. 2013, 9, 246–253, doi:10.3762/bjoc.9.29

N-Heterocyclic carbene–palladium catalysts for the direct arylation of pyrrole derivatives with aryl chlorides

  1. Ismail Özdemir,
  2. Nevin Gürbüz,
  3. Nazan Kaloğlu,
  4. Öznur Doğan,
  5. Murat Kaloğlu,
  6. Christian Bruneau and
  7. Henri Doucet
  • Full Research Paper
  • Published 12 Feb 2013

Beilstein J. Org. Chem. 2013, 9, 303–312, doi:10.3762/bjoc.9.35

  • Full Research Paper
  • Published 20 Mar 2013

  • PDF

  • Supp. Info

Beilstein J. Org. Chem. 2013, 9, 585–593, doi:10.3762/bjoc.9.63

Keep Informed

RSS Feed

Subscribe to our Latest Articles RSS Feed.

Subscribe

Follow the Beilstein-Institut

LinkedIn

Twitter: @BeilsteinInst