Bifunctional catalysis

  1. editorImage
  1. Editor: Prof. Darren J. Dixon
    University of Oxford

Bifunctional catalysis concerns the use of low molecular weight, structurally defined molecules possessing two distinct functional groups to bring about new reactivity or selectivity in a reaction of interest. The reactions are typically polar addition reactions of pronucleophiles and electrophiles where, ideally, simple low-cost starting materials are converted into high-value, stereochemically defined products through the action of the bifunctional catalyst system. The present Thematic Series serves to highlight the current state-of-the-art of bifunctional catalysis from new bifunctional catalyst design and development, their application in new asymmetric metholodgy development, to their application in natural product and drug target synthesis.

See also the Thematic Series:
Strategies in asymmetric catalysis
Sustainable catalysis

Bifunctional catalysis

  1. Darren J. Dixon
  • Editorial
  • Published 25 May 2016

Beilstein J. Org. Chem. 2016, 12, 1079–1080, doi:10.3762/bjoc.12.102

  • Full Research Paper
  • Published 14 Dec 2015

  • PDF

  • Supp. Info

Beilstein J. Org. Chem. 2015, 11, 2577–2583, doi:10.3762/bjoc.11.277

Bifunctional phase-transfer catalysis in the asymmetric synthesis of biologically active isoindolinones

  1. Antonia Di Mola,
  2. Maximilian Tiffner,
  3. Francesco Scorzelli,
  4. Laura Palombi,
  5. Rosanna Filosa,
  6. Paolo De Caprariis,
  7. Mario Waser and
  8. Antonio Massa
  • Full Research Paper
  • Published 15 Dec 2015

  • PDF

  • Supp. Info

Beilstein J. Org. Chem. 2015, 11, 2591–2599, doi:10.3762/bjoc.11.279

Catalytic asymmetric formal synthesis of beraprost

  1. Yusuke Kobayashi,
  2. Ryuta Kuramoto and
  3. Yoshiji Takemoto
  • Full Research Paper
  • Published 18 Dec 2015

Beilstein J. Org. Chem. 2015, 11, 2654–2660, doi:10.3762/bjoc.11.285

  • Full Research Paper
  • Published 04 Feb 2016

Beilstein J. Org. Chem. 2016, 12, 198–203, doi:10.3762/bjoc.12.22

  • Letter
  • Published 11 Feb 2016

Beilstein J. Org. Chem. 2016, 12, 253–259, doi:10.3762/bjoc.12.27

Organocatalytic asymmetric Henry reaction of 1H-pyrrole-2,3-diones with bifunctional amine-thiourea catalysts bearing multiple hydrogen-bond donors

  1. Ming-Liang Zhang,
  2. Deng-Feng Yue,
  3. Zhen-Hua Wang,
  4. Yuan Luo,
  5. Xiao-Ying Xu,
  6. Xiao-Mei Zhang and
  7. Wei-Cheng Yuan
  • Full Research Paper
  • Published 16 Feb 2016

Beilstein J. Org. Chem. 2016, 12, 295–300, doi:10.3762/bjoc.12.31

  • Full Research Paper
  • Published 18 Feb 2016

Beilstein J. Org. Chem. 2016, 12, 309–313, doi:10.3762/bjoc.12.33

  • Full Research Paper
  • Published 24 Feb 2016

Beilstein J. Org. Chem. 2016, 12, 343–348, doi:10.3762/bjoc.12.37

Cupreines and cupreidines: an established class of bifunctional cinchona organocatalysts

  1. Laura A. Bryant,
  2. Rossana Fanelli and
  3. Alexander J. A. Cobb
  • Review
  • Published 07 Mar 2016

  • PDF

Beilstein J. Org. Chem. 2016, 12, 429–443, doi:10.3762/bjoc.12.46

(Thio)urea-mediated synthesis of functionalized six-membered rings with multiple chiral centers

  1. Giorgos Koutoulogenis,
  2. Nikolaos Kaplaneris and
  3. Christoforos G. Kokotos
  • Review
  • Published 10 Mar 2016

  • PDF

Beilstein J. Org. Chem. 2016, 12, 462–495, doi:10.3762/bjoc.12.48

The aminoindanol core as a key scaffold in bifunctional organocatalysts

  1. Isaac G. Sonsona,
  2. Eugenia Marqués-López and
  3. Raquel P. Herrera
  • Review
  • Published 14 Mar 2016

  • PDF

Beilstein J. Org. Chem. 2016, 12, 505–523, doi:10.3762/bjoc.12.50

Supported bifunctional thioureas as recoverable and reusable catalysts for enantioselective nitro-Michael reactions

  1. José M. Andrés,
  2. Miriam Ceballos,
  3. Alicia Maestro,
  4. Isabel Sanz and
  5. Rafael Pedrosa
  • Full Research Paper
  • Published 01 Apr 2016

  • PDF

  • Supp. Info

Beilstein J. Org. Chem. 2016, 12, 628–635, doi:10.3762/bjoc.12.61

  • Letter
  • Published 05 Apr 2016

Beilstein J. Org. Chem. 2016, 12, 643–647, doi:10.3762/bjoc.12.63

Asymmetric α-amination of 3-substituted oxindoles using chiral bifunctional phosphine catalysts

  1. Qiao-Wen Jin,
  2. Zhuo Chai,
  3. You-Ming Huang,
  4. Gang Zou and
  5. Gang Zhao
  • Full Research Paper
  • Published 15 Apr 2016

Beilstein J. Org. Chem. 2016, 12, 725–731, doi:10.3762/bjoc.12.72

  • Review
  • Published 09 May 2016

  • PDF

Beilstein J. Org. Chem. 2016, 12, 918–936, doi:10.3762/bjoc.12.90

Towards the total synthesis of keramaphidin B

  1. Pavol Jakubec,
  2. Alistair J. M. Farley and
  3. Darren J. Dixon
  • Letter
  • Published 30 May 2016

Beilstein J. Org. Chem. 2016, 12, 1096–1100, doi:10.3762/bjoc.12.104

  • Letter
  • Published 20 Jul 2016

Beilstein J. Org. Chem. 2016, 12, 1551–1556, doi:10.3762/bjoc.12.149

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