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Self-optimisation and model-based design of experiments for developing a C–H activation flow process

Alexander Echtermeyer1,2, Yehia Amar2, Jacek Zakrzewski2 and Alexei Lapkin2,§
1Aachener Verfahrenstechnik – Process Systems Engineering, RWTH Aachen University, Aachen, Germany
2Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom
Email of corresponding author Corresponding author email     
§ + 44 1223 334796
This article is part of the Thematic Series "Automated chemical synthesis".
Guest Editor: I. R. Baxendale
Beilstein J. Org. Chem. 2017, 13, 150–163.

Part of Thematic Series

Automated chemical synthesis
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© 2017 Echtermeyer et al.; licensee Beilstein-Institut.
This is an Open Access article under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (