Microfluidic manufacturing of different niosomes nanoparticles for curcumin encapsulation: Physical characteristics, encapsulation efficacy, and drug release

Scholarly Works

• Wang, S.; Zhou, Z.; Yang, S.; Guo, Z.; Le, T.; Wu, J.; Guan, Z.; Liu, W.; Wu, W. Research Progress in Essential Oil Nanodelivery Systems. Current Nanoscience 2025, 21, 777–798. doi:10.2174/0115734137293979240709113456
• Naderi, M.; Saidi, S.; Barani, M. Advancements in microfluidic-based synthesis of niosomes for cancer and infection therapy: A comprehensive review. Journal of Molecular Liquids 2025, 434, 128048. doi:10.1016/j.molliq.2025.128048
• Jaber, S. A.; Saadh, M.; Abuhassan, Q.; Obeid, M. A. Curcumin-loaded Niosomes Prepared by Microfluidic Mixing; Characterization and Cytotoxicity Evaluation. Journal of Pharmaceutical Innovation 2025, 20. doi:10.1007/s12247-025-10003-w
• Amer, A. A.; Bingle, L.; Chaw, C. S.; Elkordy, A. A. Development of Vancomycin, a Glycopeptide Antibiotic, in a Suitable Nanoform for Oral Delivery. Molecules (Basel, Switzerland) 2025, 30, 1624. doi:10.3390/molecules30071624
• Lens, M. Niosomes as Vesicular Nanocarriers in Cosmetics: Characterisation, Development and Efficacy. Pharmaceutics 2025, 17, 287. doi:10.3390/pharmaceutics17030287
• Abdeljaber, S. N.; Aljabali, A. A.; Altrad, B.; Obeid, M. A. Silencing c-myc gene by siRNA delivered by cationic niosomes in MCF-7 cells. The Journal of pharmacy and pharmacology 2024, 77, 658–667. doi:10.1093/jpp/rgae146
• Rostami, E. Investigation of Alginate-Chitosan nanoparticles As a Drug Carrier for Levothyroxine. Jundishapur Journal of Natural Pharmaceutical Products 2024, 19. doi:10.5812/jjnpp-150307
• Zam, W.; Zahi, M. R.; El Hattab, M. Current State of Scientific Knowledge on Curcumin Encapsulation and Applications. Recent advances in food, nutrition & agriculture 2024, 16, 315–333. doi:10.2174/012772574x330008240827052241
• Talebi, M.; Bozorgchami, N.; Almasi Ghale, R.; Esmaeeli, H.; Moosavizadeh, A.; Aghajani, A.; Far, B. F.; Aminzadeh, S. The emerging applications of niosome as a nanotechnology-based approach in vaccine delivery. Vacunas (English Edition) 2024, 25, 374–384. doi:10.1016/j.vacune.2024.08.008
• Talebi, M.; Bozorgchami, N.; Almasi Ghale, R.; Esmaeeli, H.; Moosavizadeh, A.; Aghajani, A.; Far, B. F.; Aminzadeh, S. The emerging applications of niosome as a nanotechnology-based approach in vaccine delivery. Vacunas 2024, 25, 374–384. doi:10.1016/j.vacun.2024.04.002
• Aljabali, A. A. A.; Tambuwala, M. M.; Obeid, M. A. Microfluidic Manufacturing of Niosomes. AAPS Introductions in the Pharmaceutical Sciences; Springer Nature Switzerland, 2024; pp 77–108. doi:10.1007/978-3-031-60717-2_4
• Xu, X.; Tang, Q.; Gao, Y.; Chen, S.; Yu, Y.; Qian, H.; McClements, D. J.; Cao, C.; Yuan, B. Recent developments in the fabrication of food microparticles and nanoparticles using microfluidic systems. Critical reviews in food science and nutrition 2024, 65, 2199–2213. doi:10.1080/10408398.2024.2329967
• Al-Kofahi, T.; Altrad, B.; Amawi, H.; Aljabali, A. A.; Abul-Haija, Y. M.; Obeid, M. A. Paclitaxel-loaded niosomes in combination with metformin: development, characterization and anticancer potentials. Therapeutic delivery 2024, 15, 109–118. doi:10.4155/tde-2023-0089
• Aljabali, A. A. A.; Obeid, M. A.; Mishra, V.; El-Tanani, M.; Tambuwala, M. M. Customizable Microfluidic Devices: Progress, Constraints, and Future Advances. Current drug delivery 2024, 21, 1285–1299. doi:10.2174/0115672018264064231017113813
• Al Jayoush, A. R.; Hassan, H. A.; Asiri, H.; Jafar, M.; Saeed, R.; Harati, R.; Haider, M. Niosomes for nose-to-brain delivery: A non-invasive versatile carrier system for drug delivery in neurodegenerative diseases. Journal of Drug Delivery Science and Technology 2023, 89, 105007. doi:10.1016/j.jddst.2023.105007
• Ghumman, S. A.; Ijaz, A.; Noreen, S.; Aslam, A.; Kausar, R.; Irfan, A.; Latif, S.; Shazly, G. A.; Shah, P. A.; Rana, M.; Aslam, A.; Altaf, M.; Kotwica-Mojzych, K.; Bin Jardan, Y. A. Formulation and Characterization of Curcumin Niosomes: Antioxidant and Cytotoxicity Studies. Pharmaceuticals (Basel, Switzerland) 2023, 16, 1406. doi:10.3390/ph16101406
• Obeid, M. A.; Ogah, C. A.; Ogah, C. O.; Ajala, O. S.; Aldea, M. R.; Gray, A. I.; Igoli, J. I.; Ferro, V. A. Formulation and evaluation of nanosized hippadine-loaded niosome: Extraction and isolation, physicochemical properties, and in vitro cytotoxicity against human ovarian and skin cancer cell lines. Journal of Drug Delivery Science and Technology 2023, 87, 104766. doi:10.1016/j.jddst.2023.104766
• Fuciños, C.; Rodríguez-Sanz, A.; García-Caamaño, E.; Gerbino, E.; Torrado, A.; Gómez-Zavaglia, A.; Rúa, M. L. Microfluidics potential for developing food-grade microstructures through emulsification processes and their application. Food research international (Ottawa, Ont.) 2023, 172, 113086. doi:10.1016/j.foodres.2023.113086
• Martins, J. P.; Santos, H. A. Microfluidics as a Tool for the Synthesis of Advanced Drug Delivery Systems. Advanced Clinical Pharmacy - Research, Development and Practical Applications; Springer International Publishing, 2023; pp 321–364. doi:10.1007/978-3-031-26908-0_13
• Seyyedi Zadeh, E.; Ghanbari, N.; Salehi, Z.; Derakhti, S.; Amoabediny, G.; Akbari, M.; Asadi Tokmedash, M. Smart pH-responsive magnetic graphene quantum dots nanocarriers for anticancer drug delivery of curcumin. Materials Chemistry and Physics 2023, 297, 127336. doi:10.1016/j.matchemphys.2023.127336

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