Doxorubicin-loaded human serum albumin nanoparticles overcome transporter-mediated drug resistance in drug-adapted cancer cells

Hannah Onafuye,
Sebastian Pieper,
Dennis Mulac,
Jindrich Cinatl Jr.,
Mark N. Wass,
Klaus Langer and
Martin Michaelis

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Published 14 Aug 2019

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1. Figure 1: SEM confirmed the spherical shape and narrow size distribution of doxorubicin-loaded HSA (100%) nan...
  
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2. Figure 2: Doxorubicin sensitivity of UKF-NB-3, its doxorubicin-adapted sub-line UKF-NB-3^rDOX²⁰ and its vincri...
  
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3. Figure 3: Effects of doxorubicin (Dox) applied as a solution or incorporated into human serum albumin (HSA) n...
  
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4. Figure 4: Fold sensitisation to doxorubicin by doxorubicin-bound nanoparticles (NPs). Values are expressed as...
  
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5. Figure 5: Doxorubicin (Dox) concentrations that reduce neuroblastoma cell viability by 50% (IC₅₀) in the pres...
  
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Beilstein J. Nanotechnol. 2019, 10, 1707–1715, doi:10.3762/bjnano.10.166

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Tuning the performance of vanadium redox flow batteries by modifying the structural defects of the carbon felt electrode

Ditty Dixon,
Deepu Joseph Babu,
Aiswarya Bhaskar,
Hans-Michael Bruns,
Joerg J. Schneider,
Frieder Scheiba and
Helmut Ehrenberg

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Published 13 Aug 2019

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1. Figure 1: Raman spectra obtained for pristine as well as N₂-plasma-treated sample.
  
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2. Figure 2: XPS results obtained for pristine and N₂-plasma-treated samples. a) Survey scan for the N₂-plasma-t...
  
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3. Figure 3: Schematic representation of N-doping induced by N₂ plasma treatment in a graphite lattice.
  
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4. Figure 4: SEM images of a) pristine and b) N₂-plasma-treated samples.
  
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5. Figure 5: CV curves obtained for the pristine and the N₂-plasma-treated sample: a) negative redox reaction, b...
  
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6. Figure 6: Single-cell measurement results with pristine (green) and N₂-plasma-treated samples (red). a) Maxim...
  
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7. Figure 7: Evolution of efficiency and capacity retention during long-term cycling with a N₂-plasma-treated sa...
  
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Beilstein J. Nanotechnol. 2019, 10, 1698–1706, doi:10.3762/bjnano.10.165

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Precise local control of liquid crystal pretilt on polymer layers by focused ion beam nanopatterning

Maxim V. Gorkunov,
Irina V. Kasyanova,
Vladimir V. Artemov,
Alena V. Mamonova and
Serguei P. Palto

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Published 12 Aug 2019

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1. Figure 1: Schematic of a 2 μm periodic stripe pattern imprinted in the rubbed PI layer (rubbing direction sho...
  
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2. Figure 2: Exemplary PLM images in crossed polarisers (oriented as indicated by the white arrows) of the LC ce...
  
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3. Figure 3: (a) The relative optical retardation (a) measured at a wavelength of 546 nm, and the pretilt angle ...
  
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4. Figure 4: Schematic of the LC orientation on the striped pattern: The molecules are anchored in-plane along t...
  
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Beilstein J. Nanotechnol. 2019, 10, 1691–1697, doi:10.3762/bjnano.10.164

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Layered double hydroxide/sepiolite hybrid nanoarchitectures for the controlled release of herbicides

Ediana Paula Rebitski,
Margarita Darder and
Pilar Aranda

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Published 09 Aug 2019

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1. Figure 1: Schematic representations of (A) sepiolite and (B) layered double hydroxide structures, (C) molecul...
  
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2. Figure 2: (A) XRD patterns and (B) FTIR spectra of individual components (sepiolite, LDH, and MCPA), MCPA_ie-L...
  
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3. Figure 3: FE-SEM images of (A) sepiolite, (B) LDH/Sep1:1_150C and (C) MCPA_ie-LDH/Sep1:1_150C nanoarchitecture...
  
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4. Figure 4: XRD patterns of hybrid nanoarchitectures prepared by coprecipitation of MgAl-LDH in the presence of...
  
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5. Figure 5: (A) FTIR (3800 to 3600 cm⁻¹ region) and (B) ²⁹Si MAS NMR spectra of neat sepiolite and hybrid nanoa...
  
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6. Figure 6: FE-SEM images of (A) MCPA-LDH/Sep2:1_150C, (B) MCPA-LDH/Sep1:1_150C, (C) MCPA-LDH/Sep0.5:1_60C, (D)...
  
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7. Figure 7: (A) In vitro release of MCPA from the hybrid formulations in deionized water (pH approx. 5.5), and ...
  
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8. Figure 8: (A) In vitro release of MCPA encapsulated in the A-Z@MCPA-LDH/Sep bionanocomposite system over a pe...
  
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Beilstein J. Nanotechnol. 2019, 10, 1679–1690, doi:10.3762/bjnano.10.163

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Nanoporous smartPearls for dermal application – Identification of optimal silica types and a scalable production process as prerequisites for marketed products

David Hespeler,
Sanaa El Nomeiri,
Jonas Kaltenbach and
Rainer H. Müller

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Published 08 Aug 2019

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1. Figure 1: From left to right: rutin/ethanol solution, silica dispersed in rutin solution attached to the rota...
  
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2. Figure 2: Macroscopic appearance of rutin-loaded silica powders, with decreasing agglomeration tendency from ...
  
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3. Figure 3: DSC thermograms of crystalline rutin, unloaded silica, a physical mixture of 5% rutin, to be compar...
  
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4. Figure 4: XRD of rutin, unloaded silica (SP53D), and a physical mixture (3% rutin) in comparison to the maxim...
  
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5. Figure 5: DSC thermograms (left) and XRD diffractograms (right) for selected silica nanoparticles, all loaded...
  
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6. Figure 6: Upper row: light microscopy pictures of silica XDP 3050 unloaded (left), loaded with the maximum am...
  
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7. Figure 7: Description of the silica particle loading mechanism showing the distribution of differently filled...
  
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8. Figure 8: Recovered fraction of rutin after extraction from silica SP53D (left) and 72 FP (right) with rutin ...
  
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9. Figure 9: In situ determined saturation solubility of rutin raw active agent powder (lower curves, red) and a...
  
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Beilstein J. Nanotechnol. 2019, 10, 1666–1678, doi:10.3762/bjnano.10.162

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Giant magnetoresistance ratio in a current-perpendicular-to-plane spin valve based on an inverse Heusler alloy Ti₂NiAl

Yu Feng,
Zhou Cui,
Bo Wu,
Jianwei Li,
Hongkuan Yuan and
Hong Chen

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Published 08 Aug 2019

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1. Figure 1: Schematic illustration of a Ti₂NiAl/Ag/Ti₂NiAl device with different atomic terminated interfaces. ...
  
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2. Figure 2: The calculated atomic spin magnetic moment of Ti₂NiAl/Ag/Ti₂NiAl CPP-SV at different atomic layers....
  
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3. Figure 3: Density of states of the interface of the Ti₂NiAl/Ag/Ti₂NiAl device with different atomic terminate...
  
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4. Figure 4: Transmission coefficient versus electron energy in the parallel magnetization configuration (PC) an...
  
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5. Figure 5: The k_//-resolved transmission coefficients at the Fermi level of the Ti₂NiAl/Ag/Ti₂NiAl CPP-SV with...
  
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Beilstein J. Nanotechnol. 2019, 10, 1658–1665, doi:10.3762/bjnano.10.161

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Stationary beam full-field transmission helium ion microscopy using sub-50 keV He⁺: Projected images and intensity patterns

Michael Mousley,
Santhana Eswara,
Olivier De Castro,
Olivier Bouton,
Nico Klingner,
Christoph T. Koch,
Gregor Hlawacek and
Tom Wirtz

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Published 07 Aug 2019

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1. Figure 1: Schematic of the transmission helium ion microscope (THIM).
  
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2. Figure 2: For a BN sample, the voltage of Lens 2 was decreased from (A) to (E). A) A shadow image, B) a highe...
  
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3. Figure 3: Examples of overfocus bright outline deflection patterns (A and D), underfocus spot patterns (B and...
  
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4. Figure 4: A) HIM SE image with charge compensation by electron flooding and B) HIM SE image without charge co...
  
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5. Figure 5: A) A THIM through-focus series of the MgO sample (coated with 10 nm Au on both sides) produced by d...
  
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Beilstein J. Nanotechnol. 2019, 10, 1648–1657, doi:10.3762/bjnano.10.160

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Subsurface imaging of flexible circuits via contact resonance atomic force microscopy

Wenting Wang,
Chengfu Ma,
Yuhang Chen,
Lei Zheng,
Huarong Liu and
Jiaru Chu

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Published 07 Aug 2019

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1. Figure 1: (a) Schematic illustration of CR-AFM imaging on the flexible circuit sample. (b) An enlarged sectio...
  
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2. Figure 2: Subsurface imaging of the flexible circuit sample with a top layer thickness of 52 nm measured via ...
  
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3. Figure 3: Influence of the applied force on CR-AFM subsurface imaging of the flexible circuit sample with a 5...
  
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4. Figure 4: Influence of cantilever stiffness on CR-AFM subsurface imaging of the flexible circuit sample with ...
  
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5. Figure 5: The influence of cantilever oscillation eigenmode on CR-AFM subsurface imaging of a flexible circui...
  
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6. Figure 6: Influence of cover thickness on CR-AFM subsurface imaging of the circuit sample. (a–e) Frequency im...
  
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7. Figure 7: Influence of thickness and material properties of each layer on subsurface imaging of the circuit p...
  
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8. Figure 8: Optimization of CR-AFM subsurface imaging on a flexible circuit sample. (a,b) CR-AFM frequency imag...
  
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9. Figure 9: Subsurface imaging of defects in the buried circuit pattern using CR-AFM. (a) Schematic illustratio...
  
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Beilstein J. Nanotechnol. 2019, 10, 1636–1647, doi:10.3762/bjnano.10.159

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Effects of surface charge and boundary slip on time-periodic pressure-driven flow and electrokinetic energy conversion in a nanotube

Mandula Buren,
Yongjun Jian,
Yingchun Zhao,
Long Chang and
Quansheng Liu

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Published 06 Aug 2019

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1. Figure 1: Schematic drawing of the circular nanotube.
  
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2. Figure 2: (a) The coupling influences of the boundary slip and the zeta potential on the velocity amplitude (...
  
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3. Figure 3: (a, b) Contours of the electrokinetic energy conversion efficiency (ω = 10⁻¹ MHz, b₀ = 40 nm) for d...
  
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4. Figure 4: (a) Variation of η as function of ζ at different values of a and n₀ (ω = 10⁻¹ MHz, b₀ = 20 nm) unde...
  
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Beilstein J. Nanotechnol. 2019, 10, 1628–1635, doi:10.3762/bjnano.10.158

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Upcycling of polyurethane waste by mechanochemistry: synthesis of N-doped porous carbon materials for supercapacitor applications

Christina Schneidermann,
Pascal Otto,
Desirée Leistenschneider,
Sven Grätz,
Claudia Eßbach and
Lars Borchardt

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Published 06 Aug 2019

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1. Figure 1: Upcycling approach consisting of high-energy ball milling and carbonization of a mixture of PU foam...
  
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2. Figure 2: (A, C) Nitrogen adsorption/desorption (filled symbols/empty symbols) isotherms (measured at −196 °C...
  
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3. Figure 3: (A) Water vapor sorption isotherms (adsorption/desorption = filled symbols/empty symbols) measured ...
  
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4. Figure 4: (A) Cyclic voltammogram measured in 1 M TEABF₄ (ACN) with a scan rate of 10 mV·s⁻¹ (solid lines) an...
  
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Beilstein J. Nanotechnol. 2019, 10, 1618–1627, doi:10.3762/bjnano.10.157

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